Connective Tissue Flashcards
Name the different types of connective tissue
Blood Bone Loose fibrous Dense fibrous Cartilage
Describe the appearance of a fibroblast cell
Plump spindle shaped, basophillic cytoplasm, full of ribosomes and has a large nucleus
Describe the function of a fibroblast
Makes fibres and ground substance, they form all connective tissue. Also responsible for collagen and GAG production (glucosaminoglycans)
Describe the appearance of a fibrocyte
Elongated spindle shaped whispy connective tissue with a condensed nucleus
Describe the function of a fibrocyte
Maintains fibres and ground substance
Describe the components of loose connective tissue
Made up of fibrocytes that are whispy with small condensed nucleus. White space is ground substance. Fibres can be collagenous, reticular or elastic.
Describe the components of dense regular connective tissue
The fibres run vertically and there are more fibres than cells (fibrocytes). Fibres are arranged in linear bundles. (It forms tendons and ligaments)
Describe the components of dense irregular connective tissue
Lots of fibres running in every direction, there are more fibres than cells (fibrocytes).
Forms the dermis of the skin and organ capsulals
Describe the components of cartilage
Made of ground substance, cells (condroblasts) matrix (very dense) of Collagen fibre and lacunae.
Chondrocytes may be present in mature cartilage.
What is endochondrial ossification?
The process when mesemchymal stem cells become a chondroblast, then a chondrocyte which is the end stage.
Describe the components of hyaline cartilage
Chondrocytes in lacunae and a matrix (an aqueous gel containing proteoglycans). You can usually see a deep middle and superficial zone.
Define endochondrial ossification, and describe the steps
It is when bone develops from a cartilagenous model.
1 chondrocytes proliferate
2 cartilage matrix mineralises
3 chondrocytes die
4 blood vessels invade
5 osteoblasts deposit bone on cartilage matrix, which forms the primary trabeculae of bone
6 osteoclasts and osteoblasts remodel the primary trabelculae to form secondary trabaculae
Haematapoesis; define
Haematapoesis is the formation of blood cellular components. It Occurs in the liver and bone marrow in the foetus, and the red marrow of the adult bone