Connective Tissue Flashcards

1
Q

Connective Tissue Functions

A

Connect
Protect
Support

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2
Q

Connective Tissue Components

A

Made of fibers, cells and ground substance

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3
Q

Fibers

A

Provide tensile strength

Main types are collagen and elastin

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4
Q

Collagen

A

Made up of tropocollagen

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5
Q

Cells

A

Either fixed or migratory

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6
Q

Ground Substance

A

Made up of water, GAG’s and proteoglycans

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7
Q

GAG’s

A

Negatively charged and resist pressure

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8
Q

Dense Connective Tissue

A

Ligament
Tendon
Outer layer of joint capsule

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9
Q

Loose Connective Tissue

A

Adipose
Areolar tissue
Surrounds blood vessels/nerves

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10
Q

Viscoelastic Material Properties

A

Time-dependent
Rate-dependent
Hysteresis

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11
Q

Time-Dependent

A

Longer load = greater deformation

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12
Q

Rate-Dependent

A

Better resists loads applied more quickly than slow

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13
Q

Hysteresis

A

Energy dissipates due to internal friction, leading to curve of deformation

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14
Q

Creep Phenomenon

A

Strain reaches equilibrium over period of time

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15
Q

Stress-Strain Curve

A

Strain is the deformation of tissue

Stress is the load placed on the tissue

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16
Q

Toe Region

A

Minimal stress

17
Q

Elastic Region

A

Increased stress up to yield point

Elastic limit

18
Q

Plastic Region

A

Past the last limit and will have permanent deformation

19
Q

Failure Point

A

Complete rupture

20
Q

Young’s Modulus

A

How much a substance will deform in response to force

21
Q

Cortical Bone

A

Outer perimeter

Resist torsion and bending

22
Q

Cancellous Bone

A

Metabolic activity

Highly vascular

23
Q

Wolff’s Law

A

Bone is laid down in areas of high stress and resorbed in areas of low stress

24
Q

Cartilage Zone

A

Superficial (horizontal collagen) (1)
Transitional zone (arch-like collagen) (2)
Deep zone (perpendicular collagen) (3)
Zone of calcified cartilage (4)

25
Q

Tendons

A
Type 1 collagen fibers
Oriented in line of tension
Transmit muscle force to bones
Poor blood supply
Myotendinous junction is weakest
26
Q

Ligaments

A

Type 1 collagen fibers
Oriented in line of tension
Provide joint stabilization at end range
Bone to bone

27
Q

Bone Optimal Stimulus

A

Loading along axis of bone

28
Q

Cartilage Optimal Stimulus

A

Intermittent compression and decompression

29
Q

Ligaments/Tendons

A

Tensile stress in the line of fiber orientation

30
Q

Aging on Connective Tissue

A

Decreased water content, elasticity, maximal strength and adaptability

31
Q

Diabetes on Connective Tissue

A

Increased cross-linkage of fibers (greater stiffness and risk for damage)

32
Q

Immobilization on Connective Tissue

A
Osteoporosis
Decrease water content
Atrophy of cartilage
Atrophy at MTJ (dec tendon strength)
Atrophy/disorganization of ligament fiber arrangement