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Histology > Connective tissue > Flashcards

Connective tissue Flashcards

1
Q

Name the 3 structural properties of connective tissue?

A

Tensile strength, elasticity and volume

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2
Q

Name the four main types of connective tissues?

A

connective tissue proper, cartilage, bone and blood

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3
Q

name the two fibres found in ECM

A

Collagen and elastin

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4
Q

what is collagen made up of?

A

Amino acids

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5
Q

What characteristic does collagen have in the ECM?

A

provides tensile strength

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6
Q

How many types of collagen are there?

A
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7
Q

Where is collagen I found

A

bones, tendons, organs

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8
Q

Where is collagen II found

A

hyaline cartilage

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9
Q

Where is collagen III found

A

reticular fibres (liver, uterus, bowel - tissues that must withstand stretching)

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10
Q

Where is collagen IV found

A

base membranes

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11
Q

What is the property of elastin that makes is a suitable fibre

A

elasticity

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12
Q

What is the function of elastin

A

for stretch and recoil (elastin fibrils - function like rubber)

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13
Q
A
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14
Q

What makes up the volume in there ECM

A

glycoproteins and complex carbohydrates hyaluronic acid and glucosamine

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15
Q

What two components make up ECM

A

ground substance and fibres (elastin and collagen)

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16
Q

What is in ground substance?

A

Structural glycoproteins - fibrillin (elastin) and fibronectin - binding cites for Connective tissue

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17
Q

what are integrins

A

cell adhesion molecules

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18
Q

what is the function of chondrocytes?

A

Maintain ECM in cartilage

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19
Q

function of fibroblasts

A

secrete fibres & components of ground substance

20
Q

function of odontoblasts

A

synthesis dentin in teeth

20
Q

function of adipocytes

A

maintain ECM in adipose tissue

21
Q

function of osteoclasts

A

breakdown ECM in bone

22
Q

‘blasts’ meaning

A

synsthesise

22
Q

‘cystes’ meaning

A

maintain

23
Q

clasts meaning

A

breakdown

24
Q

properties of connective tissues

A

highly vascularised, blood vessels & lymphatics, immune cells (surgery tissues for invading pathogens/cell damage)
(Except cartilage, tendons & bone)

25
Q

what are the two different groups of connective tissue proper

A

loose or dense

26
Q

what are the types of loose connective proper tissue you can get?

A

areolar, adipose and reticular

27
Q

what is areolar connective tissue proper

A

supports & binds other tissues (submucosa)

28
Q

what

A
29
Q

what is reticular tissue (loose)

A

branched (type 3 collagen)

30
Q

what are the types of dense connective proper tissue you can get?

A

regular, irregular and elastic

31
Q

what is dense regular tissue

A

run same direction (tendons & ligaments)

32
Q

what is dense irregular tissue

A

run in different direction (skin)

33
Q

what is dense elastic tissue

A

recoil after stretching (arteries, skin and lungs)

34
Q

What are the two types of skeletal connective tissue

A

Cartilage and bone

35
Q

what is fluid connective tissue

A

blood

36
Q

what is a connective tissue disorder that has oral manifestations?

A

Scurvy - lack of vitamin C (leads to defective collagen formation) Vitamin C is a co-factor of collagen synthesis.

37
Q

What physical properties does collagen have?

A

triple helix (3 amino acids - glycine, proline and hydroxyproline)

38
Q

What occurs when collagen is not present in connective tissue?

A

blood vessels, tendons and skin become fragile

39
Q

How do you treat scurvy?

A

Vitamin C supplements

40
Q

What oral manifestations will be present in a patient with untreated scurvy?

A

Left untreated, scurvy can lead to bleeding gums, loosened teeth and bleeding under your skin.

41
Q

what are the characteristics of Systemic lupus erythematosus (SLE)

A

autoimmune disease, dryness and soreness in mouth. Buccal and palatal lesions

42
Q

What are the characteristic of Sjorgrens

A

autoimmune
dry eyes & mouth
dental caries & candidiasis
Affects glands that produce tears and saliva (exocrine)

43
Q

what is adipose tissue?

A

otherwise known as body fat, is a connective tissue that extends throughout your body. It’s found under your skin (subcutaneous fat), between your internal organs (visceral fat) and even in the inner cavities of bones (bone marrow adipose tissue).

44
Q

what is the function of adipose tissue

A

They provide energy storage, insulation from extreme temperatures and cushioning around soft organs.

45
Q
A

Histology (9 decks)

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