Connective Tissue Flashcards
What does connective tissue develop from?
Mesoderm / mesenchyme
What are fibroblasts responsible for?
Production + maintenance of fibers + ground subst
What are fibroblasts @ resting stage known as?
Fibrocytes
What is the purpose of adipose cells?
Synthesis & storage of fats
What is another word for macrophages & what are the 3 shapes it forms?
Histiocytes 3 shapes : - fusiform - Stellate - spheroidal
What is the nature of macrophages?
Phagocytic
What is the key function of plasma cells?
Provide resistance to the body against disease
What are plasma cells specialized for?
Manufacture of antibodies against antigens
Where are plasma cells found abundant in?
Lamina propria of digestive & respiratory tract
What tissue are plasma cells found in?
Lymphoid tissue
Where are mast cells widely distributed?
Connective tissue,
Along Blood vessel courses
What do mast cells secrete?
- Histamine
- Serotonin
What is the precursor of all cell types called + where is it found?
Undifferentiated mesenchymal cells
- found: blood vessels
Where are pigment cells found + what is its function?
Epidermis of skin
FN: protect skin from sun ray effects
What is another name for pigment cells?
Melanocytes
What are 2 types of blood cells?
- lymphocytes
- neutrophils
What are the 3 types of fibres?
- collagen
- elastic
- reticular
What is the nature of collagen fibres?
- Inelastic
- great tensile strength
What are collagen fibres synthesized by?
Fibroblasts
What are the subunits of collagen fibres called?
Tropocollagen
How do fresh collagen fibres appear?
Colorless
How does gelatin occur?
Fibers treated with dilute acetic acid + swell up = gelatin
How many types of collagen fibres are there?
5
What is the nature of type 1 collagen fibers + where is it seen?
Thickest fibers
- seen in : bones, tendons, dermis of skin
Where are type 2 collagen fibers seen?
- Cartilages
- vitreous body of eye
Where are type 3 collagen fibers seen?
- Spleen
- lymph nodes
- bone marrow = reticular fibers
Where are type 4 collagen fibers seen?
Basement membrane