Connection Tissue Flashcards
What does the connective tissue include ? What is it bonded by ? What is the function depend on ? What are fuctions ?
What is a stroma , what does it do ? What is it composed of ?
How are embronic connective tissue, Proper, and specizlied broken into ?
What is Epithlial-Mesenchymal Transition (EMT) What is it , and what does it do ?
Whats the difference of epithelial and mesenchymal ?
In EMT in tumor progression, what is occurring ?
Embryonic Connective tissue, what is mesenchyme where is it derived from ? What region is it part of ? What does it give rise to in adults ? What is the shape ? How does it contact each other ? what is the reticular fibers ?
Embryonic connection tissue, what is the mesenchymal cells , what does it produce ? What is Pericytes ? What characteristics does it have, and what can it differentiate into ?
What are the mesechymal stem cells broken into ?
Embryonic connective tissue, what is the mucus connective tissue located ? how is it like ? How are the spindle cells organized , and what does it resemble ?
Embryonic Connective tissue, what is sarcomas ? What is malignant fibrous histiocytoma ? How does it look on EM ? Wher is it locate ? How is it treated ?
In Connective Tissue Proper, what is loose connective tissue ? What is it important in ? where is it located ? Where do most cells wander ? What is it prone to ?
Connective Tissue proper: What does the mucosa consist of ? What is it called ? Where is it located ?
Connective Tissue Proper, what are Dense irregular Connective Tissue ? Does it have ground substance ? How are the collagen fibers arranged ? What is the connection to submucosa of the GI tract ?
Flip and know which one is collagen fibers, and fibroblast ?
connective Tissue Proper, what are Dense Regular conenctive tissue ? How are they packed ?
What is tendons ? What are they attached to ? What is the arrangement, where is the projections from ? What is tendons surrounded by ? What is the endotendineum ?
Connective Tissue Proper, what is dense regular connective tissue broken into ? what are ligaments ? What are they composed of ? What is the elastic ligaments made of ??
What is aponeuroses ? What is the degree one sheet if align from the other ? What do they join one ore more ?
Connective Tissue Fibers: Collagen
What are they produced by ? The collegen fibers is noteworthy because ? How is it flexible ? What does the wavy strucutre stain with ? What does it look like in EM ?
How are Collagen fibrils packed ? How are the stregth given ? How is it made ? What is improtant about every 3rd AA ? What is Glycoprotien in collagen ?
In type 1 collagen, what does it have ? How about type 2 collagen ?
What are Collagen fibrils ? How many types of collagens ? What is homotrimeric ? What is Heterotrimeric ? Which synthesize this ? What effect does TGF-B and plattelet have ?
What about steroids do ?
How are classes of Collagen determined ? What is Fibrillar Collagens ? What is Fibril associatted collagens with interrupted triple helixes ? Hexagonal network forming collagens ? What is transmembrane collagens ? , Multiplexins, basement membrane forming collagens ?
In collagen type one and 4 and what are there characteristics ?
What is the nmoenic for this ?
SCAB
In intracellular Collagen Formation what is the responsible for ? What is rER cistenae do ? Where does hydroxylation of proline and lysine residue ascorbic acid ? What is needed for ?
What is formatin of globular head in carboxy terminus ?
Formation of procollagen triple helix on ?
Formation of H+ nd disulfide bonds for ?
What do they stabilize ?
What do they transport ?
Extracellular Collagen Formation, what is the procollagen peptidases for ? What does collagen molecules align to form ?
Collagen Formation ?
Collagen fibrils are composed of ?
Type 1 collagen fibrils contain ?
What is scurvy ? Where is it seen ? What are the symptoms ?
In Collagen Degradation there are two pathways, what is Proteolytic degradation ?
What is Collagenases ? Gelatinases? Stromelysins? Matrilysins? Membrane-type MMP, Macrophage metalloelastases ?
What is Collagen Degradation ? What is phagocytotic degradation ? What does macrophages do ?? How about Fibroblast ?
Collagenopathies is caused by ? How is it encoded ? What is osteogenesis imperfecta, and what type collagen defiency ? What is Ehlers-Danlos Type IV, what it defective of .. collagen? What is Alports’s Syndrome, and what is collagen defective
Type 1 collegan is the bone and skin so OI
Ehlers-danlos- type 4 rupture arties by pulling to much, which is type 3 collegan under scA for artories
What is Collagenopathies: Osteogensis Imperfecta ?
look at it
What is collagenopathies ; Ehlers-Danlos syndrome ?
What is Type IV of Collagenopathies : ehlers-Danlos Syndrome ?
What is Collagenopathies : Alport’s syndrome ?
What is Reticular Fibers ? what type of collagen ? How is the pattern ? Where is it found ? Where is surrounded ? What does it support ? How it produced ?
type 3 therefore A= artiries
What is Reticular Fibers ? What does the silver stain show ? Where are the reticular fibers ?
What is elastic fibers ? What is it interwoven with ? How is it stain with ? Produced by ? What is composed Elastin and Fibrillin-1 ?
Elastic ligaments are found in ?
What is Marfan’s syndrome inheritance ? What mutation ? What are deficiencies in the production and distribution ?
What are some signs ?
Marfan Syndrome Hand Test, What is it ? What is signs of this ?
Extracellular Matrix , the network is made by ? What does the ratio of molecule depend on ?
What is the main function ?
In the Ground substance, how is the substance ? When does it lose ? What are the 3 main molecules ?
in ground substance. The GAG’s Has negetive charge that ?
What does it do to water ?
What about the 7 distainct GAG with sulfate bonds ?
How is it produced ?
In the ground substance, what is hyaluronan ? What can it displace ? What does it not contain ? Other proteoglycans attach to via ?
What does it give cartilage ?
Ground Substance, what is proteoglycans ? How is appearance ? What about the core protein ? What is aggrecan ?
Ground substance, what is Multi adhesive Glycoproteins, what does it ? What is the binding site for ? What does it interact with ? What does it regulate ? What is it involved in ?
Ground Substance, multiadhesive glycoproteins,
What is fibronection, what does it do, what noteworthy about it , what is the attached site for ? What is Laminin, ?
Ground Substance, what is Tenascin ? What is Osteopontin ?
Connective Tissue Cells,
what are examples of resident cells? What are examples ?
What are examples of f wandering or transient migration? what is example ?
Connective Tisue cells:Fibroblasts
Where is synthesied ? how is the cell , how is it cytoplasm? What is myofibroblast ?
Connective Tissue Cells; Macrophages
Where do they derived from ? What are the nuclues shaped like ? What is is activated by ? what facilitate migration ?
What is the protien on the cell surface, and how it interact with ?
How does it form large aggregates ?
Connective Tissue Cells: Macrophages
What is Atherosclerosis ? What is made of , What does it cause ?
Connective Tissue Cells: macrophages
Know the atherosclerosis difference?
Connective Tissue Cells : Mast cells
Mast cells what is it ?
What are the 2 types ?
Connective Tissue Cells; Mast Cells
Mast cells granules contain histamine that is ?
What is Heparin, Leukotrienes, and Eosinophil
