Conjugation of Carbohydrates L13 Flashcards

1
Q

What is an anomeric carbon?

A

Stereoisomer

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2
Q

What are the three examples of Disaccharides?

A
  1. Maltose
  2. Sucrose
  3. Lactose
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3
Q

What does Maltose consist of?

A

2 molecules of glucose in an alpha (1-4) linkage

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4
Q

What does Lactose consist of?

A

Galactose and Glucose in beta (1-4) linkage

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5
Q

What does Sucrose consist of?

A

Glucose and fructose linked through anomeric carbons

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6
Q

Monosaccharides may combine through glycosidic linkages to form ________.

A

Polysaccharides

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7
Q

What are the 5 examples of polysaccharides?

A
  1. Starches
  2. Glycogen
  3. Cellulose
  4. Dextrans
  5. Glycosaminoglycans (GAGs)
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8
Q

What are some examples of GAGs

A
  1. Chondriotin Sulfate
  2. Keratan Sulfate
  3. Dermatan Sulfate
  4. Haparan Sulfate
  5. Heparin
  6. Hyaloronic Acid
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9
Q

What is Chondroitin Sulfate involved with?

A

Bone, Cartilage, cornea formation

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10
Q

What is Keratan Sulfate involved with?

A

Cornea, connective tissue

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11
Q

What is Dermatan Sulfate involved with?

A

Binds LDL to plasma walls

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12
Q

What is Heparan Sulfate involved with?

A

Aortic wall, basement membrane

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13
Q

What is Heparin involved with?

A

Anticoagulant

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14
Q

What is Hyaluronic Acid involved with?

A

Cell migration, lubricant

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15
Q

What enzyme defect is associated with Pompe’s?

A

Acid glucosidase

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16
Q

The enzyme defect iduronate sulfatase is associated with what syndrome?

A

Hunters

17
Q

What defect is associated with Hurler’s and Schele A?

A

Alpha-L-Iduronidase

18
Q

The enzyme defect Beta-Glucoronidase is associated wit hwaht syndrome?

A

Muclipidosis VII

19
Q

T/F: I-cell Disease only has one enzyme defect

A

FALSE