Congential Flashcards
Kartagener Syndrome
Primary ciliary dyskinesia
Left to right Dinan defect
Dextrocardia
Patent Ovale foramen
Failure of septal pretty numb and secundum defused afterbirth
Paradoxical emboli-similar to ASD
Venous Thromboembolism that enters systemic arterial circulation
What is the most common congenital cardiac anomalies
VSD - typically membrane septum
Pacemaker rate
SA
AV
Bundle of his/Purkinje/ventricles
SA>AV>Bundle of his/purkinje/ventricles
Speed of conduction
Purkinje
Atrial
Ventricle
AV
Purkinje > Atria > ventricle > AV node
Where is the AV node located?
Locate it in the posterior inferior part of the inter-atrial septum
T wave-ventricular repolarization
T-wave inversion may indicate what two things?
Ischemia or resent myocardio infarction
EKG: U-wave Indicates what
Prominent and hypokalemia
Bradycardia
Torsades de pointes
Definition Predispose Progress to Caused by Drugs (ABCDE) Congenital Treatment
Polymorphic Ventricular tachycardia
Predispose: Long QT interval
Progress: ventricular fibrillation
Causes: Drug-induced long QT Anti-arrhythmic (class 1A, III) Antibiotic (macrolide) Anti-Cychotic (Haloperidol) Antidepressant TCAs Anti-Emetics (Ondansetron)
To: Magnesium sulfate
Congenital long QT syndrome
Inherit disorder of myocardial repolarization, typically do to ion channel defects
increased risk of sudden cardiac death due to Torsades de pointes
Romano-Ward syndrome
Jervell and Lange-Nelson syndrome
Romano-Ward syndrome
AD, pure cardinal phenotype
No deafness
Jervell and Lange-Nelson syndrome
AR
Sensorineural deafness
Brugada syndrome
Prevention?
Autosomal Dominant
Most common in Asian male
Pseudo-RBBB + ST elevation V1-V3
Increased risk of ventricular tech arrhythmias and sudden cardiac death
Sudden cardiac death prevention: implantable cardio converter defibrillator
Wolffe-Parkinson-White syndrome
May result in reentry circuit into what type of tachycardia?
Most common type of ventricular Pre-excitation syndrome
Abnormal fast accessory conduction pathway from atrial to ventricle (bundle of Kent) bypasses the rate slowing AV node into ventricle begins to partially depolarize earlier —> delta waves with widened QRS complex and shortened PR interva
reentry circuit —> supraventricular tachycardia
How does the myocardiocyted differ from skeletal muscles (3)
Myocardial sites have a plateau, requires calcium to increase calcium release from the sarcolemma reticulum, cells are interconnected by gap junctions.
The lung vasculatures are very unique and that hypoxia causes what?
And contrast, all other organs cause?
In hypoxia, the long vasculature will constrict. Shunting more blood to the better ventilating lungs.
All other organs will vasodilatate
Blood in the umbilical vein has a PO2 of _____.
what is the blood percentage saturated with oxygen leaving the placenta into the fetus?
30mmHg
80%