Congenital Inf

Question 1

Congenital toxoplasmosis

Classic triad of Sabin pinkerton

Answer 1

Chorioretinitis
Hydrocephalus
Cerebral calcifications

Question 2

Diagnosis in pregnant women congenital toxoplasmosis

Answer 2

Seroconversion high levels of IgG > 300 IU/ml

Amniocentesis : DNA t gondii PCR

Question 3

Primary inf during pregnancy: toxoplasmosis

Answer 3

spiramycin every 3 weeks

Question 4

Congenital toxxo treatment

Answer 4

12-18 months with pyrimethamine and sulfadiazine / sulfadoxine and folinic acid

Question 5

Congenital rubella syndrome

Answer 5

Microcephaly, PDA, cataracts (salt and pepper)

Blueberry muffin 1- rubella
2 neuroblastoma
3- CMV

Question 6

What is the most common congenital viral inf ?

Answer 6

CMV (1-2%)

Question 7

Treatment of CMV

Answer 7

Gancyclovir iv

Valacyclovir iv and per os

Question 8

Treatment of pregnant women with genital herpes

Answer 8

Acyclovir 4 weeks before birth

Question 9

Congenital syphilis treatment in pregnancy and in newborns

Answer 9

Pregnancy: procaine penicillin
Newborns: penicillin G