congenital diseases and tumours of the repro tract

Question 1

What is a Transmissable Venereal tumour?

Answer 1

• AKA stickers syndrome
• transplantable tumour of the external genitilia, nasal, skin, mucosa
• transmitted through coitus, sniffing etc
• rapid growth for 1-2 months
• then regresses after 6 months (unless immunosuppressed)
• cells - histiocytic
• cells are transplanted and grow like a graft

Question 2

Where can the transmissable venereal tumour spread to?

Answer 2

• inguinal lymph nodes

Question 3

What tumour is this?

Answer 3

• transmissable venereal tumour
• round cell tumour
• histiocytic

Question 4

What are the majority of germ cell neoplasms?

Answer 4

• benign undifferentiated neoplasms - dysgerminoma
• benign with somatic differentiation - teratoma

Question 5

What is this?

Answer 5

• ovarian teratomas
• cysts filled with mucoid material
• keratinized ep

Question 6

What do granulosa cell neoplasms cause in different species?

Answer 6

• mostly non-malignant - increased chance with age
• most common ovarian tumour - cows, mares
• more likley to be be malignant and metastize in dogs
• GCs produce inhibin - stops FSH production - may get atrophy of the contralateral ovary
• produce oestrogens and androgens
• altered oestrus cycles, anoestus, continous oestruses
• Dogs, cats - hyperoestogenism - vulvar swelling, vaginal discharge, intermittent or continous oestrus
• Horses, cows - increased blood prog, oestradiol, testosterone - nymphomania, masculanisation

Question 7

What are normal presentations of granulosa cell tumours?

Answer 7

• cystic
• haemorrhages
• enlargment of ovaries
• see granulosa cells on outside
• hard

Question 8

What is this?

Answer 8

• adenoma/ adenocarcoma
• rare in all species
• risk of metastising to peritoneum
• arises from the surface epithelium - shaggy appearance
• uni or bilateral

Question 9

What uterine tumours occur?

Answer 9

• endometrial adenomas, adenosarcomas - occur in rabbits
• Leiomyoma, Leiomyosarcoma - (SM layer) - common in dogs and cats
• lymphoma - cows

Question 10

What is this?

Answer 10

• dog, uterine leiomyomas

Question 11

What uterine tumours do rabbits get?

Answer 11

• oryctolaguscuniculi
  
  • 4% - 2-3
  • 80% - 5-6
  • multiple sites
  • metastisizes- lungs, liver, abdominal serosa
• adenosarcomas - long periods of unopposed oestrogen stimulation

Question 12

What repro tumours do males get?

Answer 12

• testes
  
  • sex cord
    
    • intersitial (Leydig)
    • sertoli cell tumour
  • germ cell
    
    • seminoma
• Prostate
  
  • epithelial
    
    • benign prostatic hyperplasia adenoma
    • adenosarcoma

Question 13

What is this?

Answer 13

• leydigoma - dog
• 10% malignant
• yellow and well circumscribed tissue
• bilateral

Question 14

When is a sertiolioma tumour common?

Answer 14

• cryptochid dogs
• malignant
• feminization syndrome - oestrogens

Question 15

WHat is this?

Answer 15

• seminoma
• well circumscribed and white
• large, round cells