Congenital Abnormalities of the Kidneys Flashcards
1
Q
Give examples of congenital abnormalities of the kidneys
A
Polycystic kidney disease
Renal agenesis
Inherited glomerular disease - Allport’s syndrome, thin glomerular basement membrane disease and hereditary nephrotic syndrome
Hereditary tubulo-interstitial disease
2
Q
What investigations should be conducted for polycystic kidney disease
A
Renal ultrasound CT AP U+Es Lipid profile Urinalysis ECG Genetic testing
3
Q
What symptoms might polycystic kidney disease present with?
A
Flank/abdominal pain Renal colic Gross haematuria UTI Kidney stones Hepatic disease Palpable mass of the kidneys Early onset hypertension
4
Q
How is polycystic kidney disease managed?
A
Renoprotective strategies: Lifestyle - weight loss, smoking cessation Antihypertensives Statins Tolvaptan
5
Q
What are the potential complications of polycystic kidney disease?
A
Cardiovascular disease SAH GORD Sepsos Pregnancy complications
6
Q
Unilateral renal agenesis is associated with increased risk of what other abnormalities / conditions?
A
Mullerian duct abnormalities
Hypertension
Focal segmental glomerulosclerosis
