Conditions Random Selection

Question 1

Female 50yrs presents with weight gain, tiredness, amenorrhoea and has noticed the front of her throat is swollen. You do bloods and find a raised TSH and a low T3. What is the diagnosis and treatment?

Answer 1

Hypothyroidism

Levothyroxine

Question 2

Women presents with intolerance to the cold, loss of appetite, coarse sparse hair and heavy periods. On examination you notice xanthelasma and a puffy face. What is investigation would you like to run? most likely diagnosis?

Answer 2

Bloods for TSH and T3 levels

Hypothyroidism (puffy face and intolerance to cold common)

Question 3

Women 30 years presents with weight loss, increased appetite and ammenorrhoea. You do bloods and find a low TSH and a high T3. What is the most likely diagnosis?

Answer 3

Hyperthyroidism

Question 4

What are the treatment options for hyperthyroidism?

Answer 4

Carbimazole and propylthiouracil (to inhibit thyroid hormone production)

Propranolol to reduce sympathetic effects of thyroxine

Question 5

Women of 25 years presents with palpitations, sweating, loss of libido, and tired during the day but with lots of energy at night. On examination you notice a tremor and goitre. What is the most likely diagnosis and treatment?

Answer 5

Hyperthyroidism- intolerance to heat, due to sympathetic action on heart get tachycardia

Carbimazole
Propranolol

Question 6

Women presents with pituitary, parathyroid and pancreatic neuroendocrine tumours. There is a family history of these tumours. What condition is this lady likely to have? Treatment?

Answer 6

MEN 1

3 Ps, screen for the MEN 1 gene. It is autosomal dominant making a mutated tumour suppressor gene

Surgical removal

Question 7

What residue is most likely effected in MEN 2 ?

Answer 7

Cystine residue

Question 8

What tumours are most likely to be contracted in MEN 2?

Answer 8

Medullarlu, parathyroid and paheochromocytoma

Question 9

Man presents with retinal abnormalities, enolymphatic tumours of the middle ear and mentions hes been gettingn floating stools. What is the likely diagnosis?

Answer 9

Von hippel lindau syndrome- mutation of VHL gene causing oxygen sensitive tumours

Question 10

Man presents with cafe au lait patches, scoliosis of the spine, axillary freckling and optic gliomas. He has also been recently experiencing palpitations. What is the likley diagnosis?

Answer 10

Neurofibromatosis type 1

Phaeochromocytoma this patient is getting as a consequence