Conception & Prenatal Development Flashcards

1
Q

Oogenesis

  • Formation, maturation of an egg (ovum)
  • By 30th week of gestation, female fetus has developed all of the ova she’ll ever have
  • Eggs aren’t released by ovary until after puberty has occurred
  • Mature ovum released from ovary during ovulation

> Occurs 14 days before next menstrual period would begin

A
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2
Q

Sperm

  1. Head - penetrates through wall of ovum; enters cell & joins nucleus of ovum; starts formation of zygote
  2. Middle
  3. Tail - provides mobility (all the way to the distal 3rd of the fallopian tube)
A

Female (XX) - gives X chromosome

Male (XY) - gives X or Y chromosome

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3
Q

Ability to conceive, implant, grow, & birth

Females need ___ & ___ hormones

Male sperm undergoes physiologic changes to penetrate the egg

A

estrogen; progesterone

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4
Q

___-___ Period

Fusion of egg & sperm

First 2 weeks after conception

Zygote undergoes cellular division

Zygote enters & implants in the uterus

> 3-4 days -> ___

> implantation 6-7 days post conception (can be mistaken for start of period)

Production of ___

A

Pre-Embryonic

decidua

human chorionic gonadotropin (hCG)

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5
Q

?

Best implantation site

A

uterine fundus

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6
Q

?

___ cells develop into the placenta & fetal membranes

___ cells develop into the fetus

A

Outer

Inner

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7
Q

hCG keeps estrogen & progesterone levels increased to support pregnancy

A
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8
Q

___ Period

Beginning of the 3rd week through the 8th week post-conception

Basic structures of all major body organs are completed during this period

Organs are especially vulnerable to ___ (environmental agents that may cause damage); can also be due to a lack of “something” (e.g. folic acid)

A

Embryonic

teratogens

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9
Q

By 4 weeks, ___ closes

By 8 weeks, ___ has developed

Ears & kidneys develop at the same time

A

neural tube

spinal cord

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10
Q

Which developmental week is this?

Period is missed

Early heartbeat at 21-22 days post-conception

A

Week 3

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11
Q

Which developmental week is this?

Heart is beating

Rapid brain growth

Paddle-shaped limb development

A

Week 5

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12
Q

Which developmental week is this?

Embryo shape changes

Neural tube closure

Heart partitions into 4 chambers

Respiratory & early digestive tracts develop

Trachea & esophagus separate completely

A

Week 4

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13
Q

Which developmental week is this?

Heart completes its final 4 chamber formation

Ears & facial features begin to develop

A

Week 6

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14
Q

Which developmental week is this?

Embryo takes on a more human-like form

Refinements to all systems continue

Eyes pigmented but not covered by eyelids yet

Fingers & toes defined

External genitalia begin to differentiate but not fully distinguished until week 10

A

Week 8

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15
Q

Which developmental week is this?

Growth & refinement of all systems

Intestines grow faster than abdominal cavity; contained in umbilical cord

A

Week 7

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16
Q

___ Period

Begins at 9 weeks post-conception until birth

A

Fetal

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17
Q

Weeks 9-12

Large head that is 1/2 total length of fetus

Body catching up to grow w/the embryonic period

Fetal movement begins but detection by mother is too light

Eyes close & won’t reopen until about 26 weeks

A

Intestines move from umbilical cord into abdomen

Fetus produces urine which is excreted into amniotic sac; is 1 of the main components of amniotic fluid

By end of 12th week, fetal sex can be determined by appearance of external genitalia on ultrasound

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18
Q

Weeks 13-16

Fetal body grows rapidly

Fetal movements strengthen

Multiparous women can detect those movements

A

Experience of fetal movements - quickening

Primiparous women don’t pick up on these sensations as fetal movements; e.g. “butterflies”

Eyes & ears reach final position, appearing more “human-like”

19
Q

Weeks 17-20

Whether primiparous or multiparous, experience fetal movement

___ begins to cover the skin to protect it from amniotic fluid

___ covers the entire body & helps ↑ attach to the fetus

Minimal amounts of ↑ & ↑ at birth

___ builds up on back of neck, behind sternum, & around kidneys

* Important in thermoregulation of neonate

A

Vernix caseosa

Lanugo

vernix caseosa; lanugo

Brown fat

20
Q

Weeks 21-24

Growth & weight gain continue

Little subcutaneous fat

Lungs produce ___ (important for breathing)

> is a surface-active lipid that makes it easier for baby to breath after birth by reducing surface tension in the alveoli & preventing alveolar collapse w/each breath

Complications here can cause permanent disability & death

A

surfactant

21
Q

Weeks 25-28

24 weeks & beyond = viability

Subcutaneous fat develops under skin, assisting thermoregulation

Surfactant production up until delivery

Eyes reopen

Blood produced in ___ instead of liver & spleen

Fetus in head down position (___)

A

bone marrow

vertex

22
Q

Weeks 29-32

Skin pigments

Toenails & fingernails present

Increase in subcutaneous fat = contour shape

If born now = NICU support

A
23
Q

Weeks 33-38

Pulmonary system continues to mature

Abundant subcutaneous fat

Lanugo may still be present (it will fall out)

Vernix caseosa remains in folds & creases (in ears, groin, armpits)

A

Testes descend into scrotum

Breast tissue present on male & female babies (a baby girl can lactate & “pseduo-menstruate”; this is normal!)

24
Q

? age is about 2 weeks longer than fertilization age

Consider 38-42 weeks of development

If fertilization age is 2 weeks, this age is 4 weeks

* Pulls into account from date of menstrual period to ovulation

A

Gestational

25
Q

?

Is the age that occurs at the moment of conception

A

Fertilization

26
Q

The Auxiliary Structures

A
27
Q

The ___

Major Functions

  • Metabolic (gas exchange)
  • Transfer of substances between mother & fetus (e.g. nutrients, antibodies)
  • Endocrine (makes estrogen, progesterone, human chorionic sommatomammotropin)

* Fetal Side = ___ (texture)

* Maternal Side = ___ (texture)

A

Placenta

Smooth

Rough

28
Q

p. 212; how the placenta works
- Maternal blood enters into the intervillous space of placenta through spinal arteries in decidua
- Issues can occur at level of spiral arteries
- Approximately 150mL of maternal blood is in intervillous space at a given time

> Cycles out 3-4x/min

A
  • Blood returns through endometrial veins for elimination of fetal waste products
  • Fetal capillaries in chorionic villi are separated from direct contact w/mother’s blood

> Blood types can be incompatible

> Antibodies can transfer through placenta –> passive immunity

  • Harmful substances can transfer from mother to fetus
29
Q
A
30
Q
  • Umbilical cord connects placenta to fetus
  • Made of __ vein & ___ arteries
  • Fetal circulation –> veins carry blood ___ the heart; vein here is carrying oxygenated blood & it is a vein because it carries blood ___ the fetal heart
  • Arteries carry blood ___ from the heart; even though they carry deoxygenated blood, they are still arteries
A

1; 2

toward; to

away

31
Q

Normal Placenta

A

A marginal cord insertion or a battledore cord

* Fetus doesn’t get as much O2 & nutrients that can lead to slowed or delayed growth

32
Q

___ insertion of umbilical cord

A very high-risk situation

A “water break” is a break in the membranes

Watch client closely & no artificial rupture of membranes

A

Velamentous

33
Q

Placenta with a small accessory lobe

A ___ lobe

Doesn’t bring in as much oxygenated blood & nutrients

Risk that some could get left behind

A

succenturiate

34
Q

Fetal Membranes

2 Fetal Membranes (lie on top of one another)

___ (Inner)

___ (Outer)

A

Amnion (towards baby)

Chorion (towards mother)

35
Q

Contain Amniotic Fluid

  • Is made of fetal urine & fluids that get transported from maternal fluid across amnion
  • 500mL to 1L of fluid present at term
  • Cushions fetus against impact
  • Provides stable temperature
  • Aids in symmetrical development
A
  • Keeps membranes from adhering to fetal parts (amniotic band syndrome)
  • Gives buoyancy to fetal movement
36
Q

Too little fluid called ___ (<500mL at term)

> Due to problem w/kidneys, blockage in genitourinary tract, issue w/urethra development/formation

Too much fluid called (___)___ (can be greater than 2L at term)

> Problem w/ingestion

A

oligohydramnios

(poly)hydramnios

37
Q

an En caul birth where a fetus is born with the amniotic sac in tact

A
38
Q

Fetal Circulation

Gas exchange is occurring at level of placenta

Blood & waste products are returned to placenta by umbilical arteries

Once neonate takes first breath, mechanism of fetal circulation changes

What are the 3 fetal shunts?

A

ductus venosus

foramen ovale

ductus arteriosus

39
Q
A
40
Q

Introduction to Multifetal Pregnancy

Twins happen spontaneously in 1 in 85 pregnancies

Spontaneous triplets occur in 1 in 8100 pregnancies

A

Monozygotic vs Dizygotic

41
Q

?

1 zygote into 2 embryos who share a placenta

IVF doesn’t increase chances

Identical twins; have same gender

A

Monozygotic

mono-mono twins who share 1 placenta & 1 amniotic sac = conjoined twins

42
Q

?

2 ovum are fertilized by 2 separate sperm

Is assisted by reproductive means

Occurs in family lines

“Fraternal” twins; one can be male; one can be female

A

Dizygotic

43
Q
A