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Misc. Pharm Exams > Compounding I > Flashcards

Compounding I Flashcards

1
Q

usual BUD for powders

A

180 days

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2
Q

process of reducing the particle size of a powder

A

comminution

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3
Q

continuous rubbing or grinding of powder

A

trituration

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4
Q

uses an intervening solvent to dissolve the powder then the dissolved powder is mixed in a mortar or spread on an ointment slab to enhance evaporation of the solvent allowing the powder to recrystallize

A

pulverization by intervention

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5
Q

reduce particle size by triturating in a mortar or spatulating on an ointment slab with a small amount of liquid solvent in which the solid is not soluble

A

levigation

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6
Q

nonpreserved aqueous dosage form BUD

A

14 days, refrigerate

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7
Q

preserved aqueous dosage form BUD

A

35 days, refrigerate or room temp

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8
Q

oral nonaqueous liquids BUD

A

90 days, refrigerate or room temp

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9
Q

other nonaqueous dosage form BUD

A

180 days, refrigerate or room temp

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10
Q

rule of 7s for capsules

A

convert contents to grains
subtract grains from 7 and round
1000 mg = 15.43 grains

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11
Q

size range of capsules

A

000-5

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12
Q

what dosage forms need to be shaken

A

suspensions and emulsions

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13
Q

properties of a suspension

A

fine, uniform particles, uniform dispersion, slow settling, ease of redispersion

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14
Q

agents to increase liquid density of a suspension

A

sucrose, glycerin, sorbitol

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15
Q

agents to induce viscosity of a suspension

A

acacia, methylcellulose

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16
Q

wetting agents/surfactants in suspensions

A

glycerin, alcohol, propylene glycol

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17
Q

aw (water activity) > 0.6

A

aqueous

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18
Q

aqueous solutions include

A

syrups, aromatic waters, mucilages, aqueous acids

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19
Q

nonaqueous solutions include

A

solvents other than water
elixirs, spirits, tinctures

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20
Q

1 oz = x mL

A

29.57 mL

21
Q

mEq =

A

mg * valence / MW

22
Q

mOsmol/L =

A

(wt of substance/MW) * (# of particles) * 1000

23
Q

oils, petrolatum hydrocarbons, or waxes dispersed in an aqueous phase

A

O/W emulsions

24
Q

water or aqueous solutions dispersed in an oleaginous medium

A

W/O emulsions

25
Q

examples of hydrocarbons/oleaginous ointment bases

A

white petrolatum, white ointment, vaseline

26
Q

hydrocarbons/oleaginous ointment bases are

A

anhydrous

27
Q

examples of anhydrous/absorption ointment bases

A

hydrophilic petrolatum, anhydrous lanolin, aquabase, aquaphor, polysorb

28
Q

anhydrous/absorption ointment bases are

A

anhydrous

29
Q

examples of W/O emulsion ointment bases

A

cold cream, hydrous lanolin, hydrocream, eucerin

30
Q

W/O emulsion ointment bases are

A

hydrous

31
Q

examples of O/W emulsion ointment bases

A

dermabase, velvachol, unibase

32
Q

O/W emulsion ointment bases are

A

hydrous

33
Q

examples of water soluble ointment bases

A

PEG ointment, polybase

34
Q

water soluble ointment bases are

A

anhydrous, hydrous

35
Q

1 oz = x grams

A

28.35 g

36
Q

oleaginous suppository bases

A

cocoa butter, fattibase, hydrogenated vegetable oils

37
Q

water soluble suppository bases

A

PEG, polymers, glycerinated gelatin

38
Q

solid fillers

A

starch, lactose, cellulose powder

39
Q

semisolid fillers

A

petrolatum, mineral oil, lanolin

40
Q

liquid fillers

A

water, glycerin

41
Q

flavoring agents/sweeteners

A

aspartame, saccharin, sucralose, xylitol, mannitol, stevia

42
Q

binders

A

acacia, starch paste

43
Q

lubricants

A

PEG, glycerin, mineral oil, talc

44
Q

disintegrants

A

cellulose, starch, alginic acid

45
Q

preservatives

A

sodium benzoate, benzoic acid, benzyl alcohol, parabens, EDTA, thimerosal

46
Q

anti-foaming agents

A

simethicone

47
Q

thickening agents

A

xantham gum, guar gum, acacia, agar, gelatin, poloxamer gels, PEG, tragacanth

48
Q

levigating (wetting) agents

A

glycerin, mineral oils, glycols, PEG, propylene glycol

Misc. Pharm Exams (5 decks)

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