Compounding Flashcards
Terminology
reducing particle size to fine powder
Trituration
Terminology
wet grinding; reducing particle size of powder by mixing w/ a liquid so it will have consistency of a paste
Levigation
Terminology
adding diluent gradually in small amounts to create a homogenous mixture
Geometric dilution
Terminology
mixing different ingredients in their melting state
melt the 1 with highest melting point first
Fusion
Mannitol
Lactose
Sucrose
Sorbitol
Starch
Cellulose
Calcium phosphate
Mag Stearate
Diluents
fillers
Terminology
thicken liquid and help insoluble solids become evenly dispersed in a liquid
e.g methylcellulose, acaicia, gelatin, xanthan gum, poloxamers, agar
Suspending agents
thickening agent
Terminology
help displace air from particles to allow better mixing
e.g Alcohol, glycerin
Wetting Agents
Soluble in both oil and water= help mix oil and water
e.g TWEEN, Polysorbate, sodium/potassium oleate, PEG 400, SPAN
Emulsifying agent
Which is more water based? Cream or ointments
Cream
Which is more oil based? Cream or ointments
Ointments
Terminology
hydrophilic ointment, poorly washable
Contain oleaginous base: white petrolatum
Water in oil
HLB <10
Low= Lipophilic
Terminology
Washable ointment
contain absorption bases: aquaphor, aquabase, hydrophilic petrolatum
Oil in water
HLB > 10
High= hydrophilic
benzalkonium
benzethonium
benzoic acid
soidum benzoate
benzyl alcohol
all bisulfites
phenol
phenylethyl alcohol
ehtanol
chlorobutanol
cresol
parabens
methylparabens
thimersol
phenyl mercuric acetate
boric acid
sorbic acid/ sorbates
ascorbic acid
cetylpyridinium cl
chlorhexidine gluconate
Prervatives
Trituration
Levigation
Geometric Dilution
Make a ointment
What type of mortar and pestle do you use?
mixing liquids, creams, lotions that are oily or stain
Glass
What type of mortar and pestle do you use?
grinding/triturating
Wedgewood or Porcelain
Beyound Use Dates
Beyound Use Dates
Beyound Use Dates
Beyound Use Dates
