Astma/COPD Medications

Question 1

Brand/Generic/Class

Class & Brand Name(s) of Albuterol

Answer 1

Class: SABA
Brand Names: Ventolin, Proventil, ProAir

Question 2

Brand/Generic/Class

Class & Brand Name(s) of Levalbuterol

Answer 2

Class: SABA
Brand Name: Xopenex

Question 3

Brand/Generic/Class

Class & Brand Name(s) of Beclomethasone

Answer 3

Class: ICS
Brand Name: QVAR Redihaler

Question 4

Brand/Generic/Class

Class & Brand Name(s) of Budesonide

Answer 4

Class: ICS
Brand Name: Pulmicort

Question 5

Brand/Generic/Class

Class & Brand Name(s) of Mometasone

Answer 5

Class: ICS
Brand Name: Asmanex

Question 6

Brand/Generic/Class

Class & Brand Name(s) of Fluticasone

Answer 6

Class: ICS
Brand Name: Flovent HFA/Diskus, Arnuity Ellipta

Question 7

Brand/Generic/Class

Class & Brand Name(s) of Ciclesonide

Formulation

Answer 7

Class: ICS
Brand Name: Alvesco

MDI Solution= no shake

Question 8

Pearls

For ICS what is a important counseling point?

Answer 8

Rinse mouth after use

Question 9

Brand/Generic/Class

Class & Brand Name(s) of Salmeterol

Answer 9

Class: LABA
Brand Name: Severvent

Question 10

Brand/Generic/Class

Class & Generic Name(s) that make up Advair(Diskus/HFA) Airduo RespiClick

Answer 10

Class: LABA+ICS
Generic: Salmeterol + Futicasone

Question 11

Brand/Generic/Class

Combinations with LABA Formoterol

Brand with generic

Answer 11

ICS combos
formoterol + budesonide (Symbicort)
formoterol + mometasone (Dulera)

All MDI
FOR(moterol) M(ometasone)OM= DU(o)lera

Question 12

Brand/Generic/Class

Class & Brand Name(s) of Montelukast

Answer 12

Class: Anti-leukotriene
Brand Name: Singulair

Sing(le)air = take once a day

MOA: receptor antagonist
6 -23 months= 4 mg granules
Age 2-5= 4 mg QHS
Age 6-14= 5 mg QHS
Age ≥15 = 10 mg QHS

Question 13

Brand/Generic/Class

Class & Brand Name(s) of Zafirlukast

Answer 13

Class: Anti-leukotriene
Brand Name: Accolate

Accolate = eat later=take on empty stomach

MOA: receptor antagonist
Age ≥12= 20 mg BID
Age < 12 = 10 mg BID

Question 14

Brand/Generic/Class

Class & Brand Name(s) of Zileuton

Answer 14

Class: Anti-leukotriene
Brand Name: Zyflo, Zyflo CR

ZyfLo, ZiLeuton= monitor LFTs

MOA: pathway inhibitor
CR = BID

Question 15

Brand/Generic/Class

Class & Brand Name(s) of Omalizumab

Answer 15

Class: IgG monoclonal antibody
Brand Name: Xolair
Only for allergy related asthma

SQ Q2-4 weeks

Target IgE

Question 16

Brand/Generic/Class

IL-5 Receptor Antagonists (3)

Generic/Brand/Route/Frequency

Answer 16

• Reslisumab (Cinqair) - IV monthly
• Mepolizumab (Nucala) - SC monthly
• Benralizumab (Fasenra) -SC monthly

Question 17

Brand/Generic/Class

Class & Brand Name(s) of Ipratropium

Answer 17

Class: SAMA
Brand Name: Atrovent HFA

Question 18

Brand/Generic/Class

Combinations with SAMA Ipratropium

Brand with generic

Answer 18

SAMA+ SABA
Ipratropium + albuterol- Combibent Respimat
Nebulized Ipratropium + albuterol- Duoneb

Question 19

Brand/Generic/Class

Class & Brand Name(s) of Tiotropium

Formulation

Couseling

Answer 19

Class: LAMA
Brand Name: Spiriva HandiHaler/Respimat

Respimat= soft mist inhaler = dont shake + prime

Counseling= PTOP (Prime, Turn, Open, Press)

Question 20

Brand/Generic/Class

Class & Brand Name(s) of Umeclidinium

Answer 20

Class: LAMA
Brand Name: Incruse Ellipta

Question 21

Brand/Generic/Class

Class & Brand Name(s) of Aclidinium

Answer 21

Class: LAMA
Brand Name: Tudorza

Question 22

Brand/Generic/Class

Class & Brand Name(s) of Glycopyrrolate

Answer 22

Class: LAMA
Brand Name: Seebri

Question 23

Brand/Generic/Class

Class & Brand Name(s) of Olodaterol

Answer 23

Class: LABA
Brand Name: Striverdi Respimat

Question 24

Brand/Generic/Class

Combinations with the LABA Olodaterol

Answer 24

LABA+ LAMA (Tiotropium)= Stiolto Respimat

Respimat= soft mist inhaler= prime but not shake

Question 25

Brand/Generic/Class

Class & Brand Name(s) of Indacaterol

Answer 25

Class: LABA
Brand Name: Arcapta

Arcapta= capsule

Question 26

Brand/Generic/Class

Combinations with LABA Vilanterol

Answer 26

LABA + ICS (Fluticasone) = Breo Ellipta
LABA + LAMA (Umeclidinium)= Anoro Ellipta

Ellipta= DPI

Question 27

Brand/Generic/Class

Generics that make up Trelegy

Answer 27

Umeclidinium + Vilanterol + Fluticasone
LAMA + LABA + ICS

Question 28

Pearls

MDI Pearls

Answer 28

• HFA
• Shake
• Prime
• Breath in slow and deep
• Can use a spacer
• Hold breath for 10 secs
• Clean weekly

Question 29

Pearls

MDI that does not need to be shaken

Answer 29

• Ciclisonide (Alvesco)
• Ipratropium (Atrovent HFA)

These are solutions!!

Question 30

Pearls

DPI Pearls

Answer 30

• No priming, shaking, cleaning
• Breath in forcefully and deep
• Diskus, Ellipta, HandiHaler, RespiClick, RediHaler, Flexhaler, Twisthaler

Question 31

Pearls

DPI with capsules

Answer 31

• Indacaterol (Arcapta)
• Tiotropium (Spiriva HandiHaler)
• Gycopyrolate (Seebri)
• Indacaterol + glycopyrolate (Utibron)

Question 32

Pearls

Contraindication of DPI

Answer 32

Milk protein allergy

Question 33

Pearls

Respimat Pearls

Answer 33

• Soft mist inhaler
• No shake, no spacer
• Must prime/re-prime
  * PTOP (Prime, Turn, Open, Press)

Question 34

Pearls

Respimat Inhalers

Answer 34

• Olodaterol (Striverdi)
• Ipratropium + Albuterol (Combivent)
• Tiotropium (Spiriva)
• Olodaterol + Tiotropium (Stiolto)

Question 35

Pearls

Ellipta Pearls

Answer 35

• DPI
• In a foil- once removed only good for 6 wks

Question 36

Pearls

Roflumilast (Daliresp) Pearls

Answer 36

• Only for COPD
• PDE4 inhibitor
• Daily= Daliresp
• Major Se: Suicidality and Weight loss
• CYP3A4 Substrate–> CI in liver impairment