Components of Skin Flashcards

1
Q

Epidermis

A

stratified squamous keratinized epithelium

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2
Q

Stratum corneum

A

flattened, non-nucleated keratinized cells

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3
Q

Stratum lucidum

A

found only in thick skin, fit’s a translucent layer formed of keratinized flattened eosinophilic cells that have lost its organelles and nucleus

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4
Q

Stratum granulosum

A

cells packed with keratohyalin granules (still undergoing keratinization)

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5
Q

Stratum spinosum

A

thickest layer of the epidermis, with cells near the basal layer still undergoing mitosis (actively undergoing keratinization)

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6
Q

Stratum basale:

A

single layer of cells that attach to the basal lamina (act as stem cells)

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7
Q

Dermis:
Papillary Dermis

A

Loose connective tissue
contains dermal papillae
Type 7 collagen binds papillary dermis to basal lamina

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8
Q

Reticular Dermis

A

Dense irregular connective tissue
Contains hair follicles and glands
Sensory and sympathetic fibers

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9
Q

Hypodermis

A

Loose connective tissue
Binds skin to organs
Extensive vascular network
Contains adipose cells

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10
Q

Specialized Cells:
Keratinocytes

A

primary cell type

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11
Q

Melanocytes:

A

produce melanin
Derived from neural crest cells (ectoderm)

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12
Q

Merkel cells

A

associated with sensory nerve fibers

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13
Q

Langerhans cells

A

antigen-presenting cells
Found in stratum spinosum

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14
Q

Nerve Endings:
Non-encapsulated:
Tactile discs

A

Associated with merkel cells
Light touch

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15
Q

Nerve Endings:
Non-encapsulated:
Free nerve endings

A

goes into epidermis and dermis
Pain, temperature, itching, light touch

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16
Q

Nerve Endings:
Non-encapsulated:
Root hair plexus

A

Found at base of hair follicle
Detects hair movement

17
Q

Nerve Endings:
Encapsulated
Meissner’s Corpuscle:

A

light touch. located in dermal papillae

18
Q

Nerve Endings:
Encapsulated
Pacinian Corpuscle:

A

rapidly adapting endings sensitive to pressure and vibration
Surround unmyelinated axons
Coarse touch, sustained touch, vibrations

19
Q

Nerve Endings:
Encapsulated
Ruffini Corpuscle

A

detect stretch (tension) and twisting (torque) of the skin “like it rough”

20
Q

Nerve Endings:
Encapsulated
Krause-end bulbs

A

Thermoreceptors and mechanoreceptor