COMPONENT PREPARATION AND THERAPY Flashcards
provides the necessary/correct component that should be given to the patient
Transfusion Therapy
Has a critical value for many types of diseases and conditions
Transfusion Therapy
When targeting a certain blood component, it also allows minimization of any exposure that could lead to adverse_______ or _______
reaction or complication
Component preparation is directly from the _______; either modified or unmodified component can be prepared from it.
whole blood
A single blood donation can provide transfusion therapy to multiple patients in the form of (4)
red blood cells (RBCs), platelets, fresh-frozen plasma, and cryoprecipitate.
Most important factor to consider in preparing a component and transfusion therapy is the ___________
patient’s condition.
Equipment in the Component Manufacturing Laboratory (6)
- Centrifuge
- Plasma Expressors
- Tubing Sealers
- Sterile Connection Devices
- Storage Devices
- Quadruple Bag
Component manufacturing centrifuges are typically either large floor units or large table top units that can spin a maximum of ______ units of whole blood at once.
6 to 12 units
Purpose of centrifuge
Separate red blood cells from plasma and other components
Centrifugation depends on the following conditions (2)
o Length/duration
o Speed
Red blood cells + plasma
5,000 x g, 5 minutes (Soft Spin)
Red blood cells + platelet-rich plasma
2,000 g, 3 minutes
Harvesting platelets or Cryoprecipitate from plasma
5,000 x g, 7 minutes (Hard Spin)
*PRP (Platelet-rich plasma)
platelets are not entirely removed from the plasma
METHODS OF CENTRIFUGATION (2)
- Intermittent Flow Centrifugation (IFC)
- Continuous Flow Centrifugation (CFC)