Complications of Pregnancy 1 Flashcards
Define spontaneous miscarriage/abortion
Termination/loss of pregnancy before 24 weeks
Define still birth
Loss of pregnancy after 24 weeks
What are the categories of miscarriage?
Threatened Inevitable Partial Complete Missed Septic
What is a threatened miscarriage?
Bleeding from gravid uterus before 24 weeks with closed cervix and viable pregnancy
What is the typical presentation of threatened miscarriage?
Vaginal bleeding and pain
Viable pregnancy
Closed cervix
Spontaneous abortion can be prevented
What is an inevitable miscarriage?
PV bleeding + open cervix
What is the typical presentation of inevitable miscarriage?
Bleeding (may be heavy, may get clots), viable pregnancy and open os
What is an incomplete miscarriage?
Some production of conception are retained
What is the typical presentation of incomplete miscarriage?
PV bleeding, open cervix
What is a complete miscarriage?
Complete expulsion of products of conception
What is the typical presentation of complete miscarriage?
Cervix closed and bleeding stopped
What is a septic miscarriage?
Ascending infection after incomplete miscarriage
Infection can spread throughout pelvis
What is a missed miscarriage?
Foetal death but no expulsion of PoC
What will you see on Ex/USS if there is a missed miscarriage?
No symptoms/brown/bloody discharge, closed cervix
USS - empty gestational sac/no fetal heart seen
What are the aetiologies of miscarriages?
Abnormal conceptus - chromosomal/structural/genetic abnormalities (50%)
Uterine abnormalities - submucosal fibroids, fusion failure of Mullerian ducts
Cervical impotence
Maternal factors - DM, increased age, SLE, thyroid disease, acute maternal infection
Unknown - hormonal imbalances
Which type of fibroids distort the uterine cavity the worst?
Submucosal
What occurs in cervical impotence that leads to miscarriage?
Cervix opens prematurely with absent/minimal uterine activity and pregnancy is expelled
What factors are linked to cervical impotence?
Trauma to cervix, e.g. following dilatation of cervix or cone biopsy treatment
How can hormonal imbalances lead to miscarriage?
CL essential for survival in first 8 weeks of pregnancy
If CL removed –> abortion within 7 days
?Lower progesterone levels assoc with higher risk of miscarriage
How can acute maternal infection lead to miscarriage?
General toxic illness with high temperature can stimulate uterine activity –> loss of pregnancy
E.g. appendicitis
What is the management of threatened miscarriage?
Watch and weight, avoid strenuous exercise, weakly pelvic USS
What is the management of inevitable miscarriage?
May req. evacuation
What is the management of missed miscarriage?
Prostaglandins/misoprostol to induce cervical ripening
Surgical miscarriage
What is the management of septic miscarriage?
Antibiotics and removal of PoC
Define ectopic pregnancy
When an embryo implants in somewhere other than the uterine cavity (mostly fallopian ampulla)
What are the risk factors for ectopic pregnancy?
Alteration of the fallopian tubes, e.g. prev. ectopic in tubes, PID affecting tubes, surgery to tubes
Assisted conception
What is the presentation of ectopic pregnancy?
Amenorrhoea, +ve preg test, and other signs of pregnancy
Vaginal bleeding, GI/urinary signs, abdominal pain/tenderness over ectopic