Complicated Pregnancies Part 2 Flashcards
What is chronic hypertension?
BP 140/90 or high
PRIOR to pregnancy or before 20th week of gestation
What is gestational hypertension?
BP 140/90 or higher
AFTER 20 weeks, no proteinuria (40% will progress to pre eclampsia)
What is the early problem of preeclampsia? (How does it start?)
Defect of trophoblastic invasion due to exaggerated maternal immune response = small placenta, more fibrous blood vessels, intermittent blood flow to placenta
What is the later problems of preeclampsia?
Growing fetus places demand on placenta as a struggles with an adequate blood flow= hypoxia
Hypoxia triggers and immune response
Immune response leads to the generalized inflammation and endothelial vasospasms and capillary injury
Science and symptoms of pre-eclampsia begin
When do we give low dose aspirin
Should be initiated between 12 weeks and 28 weeks of gestation and continued daily until delivery
What type of patient would get ASA regarding prevention of preeclampsia?
History of preeclampsia
Renal disease
Auto immune disease
Type I or type II diabetes
Chronic hypertension
First pregnancy
Maternal age of 35 years or older
BMI > 30
What are some maternal complications of preeclampsia?
Seriously impacts cardiovascular system, kidneys, liver, lungs, placenta function
What are fetal complications of preeclampsia?
Small for gestational age (SGA)
Fetal hypoxia
Fetal death related to placenta abruption
Prematurity related to pre term labour
Define mild preeclampsia
BP> 140/90 on at least 2 occasions 6 hours apart
Proteinuria 1+ to 2+
What are worsening signs of preeclampsia?
Increase in generalized edema and/or NV
Worsening HA and/or blurred vision
Epigastric/shoulder or RUQ pain
Decreased UO
Hyperreflexia
Disorientation/confusion
How to diagnose severe preeclampsia?
BP> 160/110 on two occasions at least 6 hours apart while the woman is on bedrest
PLUS
Proteinuria > 5g/L in 24 hours: Two 3+ urine dip stick readings at least 4 hours apart
PLUS
one or more of the following:
Headache or visual disturbance
Pulmonary edema, or cyanosis
Epigastric or RUQ pain
Elevated liver enzymes (ALT,AST)
Elevated creatine
Thrombocytopenia (<100,000)
What does HELLP syndrome stand for?
H- Hemolysis (decreased H&h)
EL- Elevated Liver enzymes
LP- Low Platelets (thrombocytopenia)
What is HELLP syndrome?
A complication of severe preeclampsia
How do you care for severe preeclampsia
Bed rest, reduce stimuli
Magnesium sulfate IV for seizures prophylaxis
Bethamethasone IM <34 weeks for fetal lung maturity
Deliver at 34 weeks or sooner for maternal or fetal indications
What is the “cure” for preeclampsia
Delivery! Induction of labour at 37 weeks if mild, sooner if severe
C section
Magnesium sulfate for seizure prevention for severe PIH
What is eclampsia
Woman has a seizure
What does PROM stand for?
Premature rupture of membranes