Complements Association Flashcards

1
Q

C1q, C1rs, C2, C4 deficiency (classical pathway components)
predisposes to

A

immune complex disease
e.g. SLE,
Henoch-Schonlein Purpura

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2
Q

C3 deficiency leads to

A

Recurrent bacterial infection

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3
Q

C5-9 deficiency leads to ?

A

encodes the membrane attack complex (MAC)
particularly prone to Neisseria meningitidis infection

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4
Q

C5 deficiency leads to

A

recurrent diarrhoea,
wasting and

seborrhoeic dermatitis

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5
Q

C1-INH

A

strongly associated with hereditary angioedema

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