Complemento Flashcards

1
Q

Inhibe a C1q

A

C1 inhibidor, quita proteasas de serina (C1INH)

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2
Q

Degrada a la C3 convertasa

A
  • Factor acelerador de degradación (DAF)
  • CR1
  • Factor H
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3
Q

Rompe a C3b y a C4b

A

Factor I (MCP)

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4
Q

Evita formación del complejo MAC

A

Protectina (CD59)

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5
Q

Evita que C9 atraviese la membrana

A

Vitronectina y proteina S

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6
Q

Rompe a C3a y C5a

A

Carboxilpeptidasas

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7
Q

Deficiencias del complemento en general ocasionan

A

Infecciones recurrentes de bacterias gram positivas y negativas

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8
Q

Ausencia de C1q

A

Las células apoptóticas actúan como autoantígenos

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9
Q

Deficiencia de MBL

A

Infecciones respiratorias recurrentes

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10
Q

Deficiencia de C3

A

Infecciones bacterianas recurrentes

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11
Q

Inflamación por ser anafilotoxinas

A

C3a y C5a

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12
Q

Quimiotaxis

A

C5a

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13
Q

Opsonización

A

C3b

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14
Q

Amplificación del ac

A

C3b y C4b

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15
Q

Aclaración del inmuno complejo (células apoptóticas)

A

C1q

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