Complement cascade Flashcards

1
Q

What are the 3 different pathways involved in the complement pathway?

A

Classical pathway

Alternative pathway

Leptin pathway

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2
Q

What activates the classical pathway of the complement cascade?

A

Immune complexes

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3
Q

What activate the alternative pathway of the complememnt cascade?

A

The direct binding of complelemt proteins to pathogens

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4
Q

What actives the Leptin pathway of the complement cascasde?

A

Mannose Binding Leptin (MBL)

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5
Q

What is the complement cascade?

A

Process of the immune systsem that allows antibodies and phagocytes to bugger microbes

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6
Q

The 3 complement cascade pathways all activate what?

A

C3 convertase

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7
Q

When C3 convertase is activated from one of the 3 complement cascade pathways, what 2 things does it form into?

A

C3a

C3b

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8
Q

In the complement cascade, what activates C5 convertase, C3a or C3b?

A

C3b

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9
Q

The final stage of the complement cascade is C5 convertase triggering what?

A

Membrane attack complex

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10
Q

What is the formed at the end of the complement cascade?

A

Membrane attack complex

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