Complement cascade Flashcards
What are the 3 different pathways involved in the complement pathway?
Classical pathway
Alternative pathway
Leptin pathway
What activates the classical pathway of the complement cascade?
Immune complexes
What activate the alternative pathway of the complememnt cascade?
The direct binding of complelemt proteins to pathogens
What actives the Leptin pathway of the complement cascasde?
Mannose Binding Leptin (MBL)
What is the complement cascade?
Process of the immune systsem that allows antibodies and phagocytes to bugger microbes
The 3 complement cascade pathways all activate what?
C3 convertase
When C3 convertase is activated from one of the 3 complement cascade pathways, what 2 things does it form into?
C3a
C3b
In the complement cascade, what activates C5 convertase, C3a or C3b?
C3b
The final stage of the complement cascade is C5 convertase triggering what?
Membrane attack complex
What is the formed at the end of the complement cascade?
Membrane attack complex