Antibodies

Question 1

What are the functions of antibodies?

Answer 1

Direct binding (via immune complexes)
Phagocytosis 
Opsonisation 
Lysis 
Complement activation

Question 2

What are the 2 different regions on antibodies and what are their functions?

Answer 2

FAB= antigen binding

Fc= communication

Question 3

Why chain on an antibody is involved in changes in isotopes?

Answer 3

Heavy chain

Question 4

Via what process forms antibodies and increases the diversity of antibodies?

Answer 4

V(D)J recombination

Question 5

What shape is an antibody?

Answer 5

Y-shapped

Question 6

What type of bond holds the two parts of an antibody together?

Answer 6

Disulphide bond

Question 7

What are the 2 different classifications of antibodies?

Answer 7

Soluble

Membrane bound

Question 8

What are the 5 different antibody Isotopes?

Answer 8

IgM
IgA
IgG
IgD
IgE

Question 9

What antibody isotope is the largest, is a pentameter shape, is commonest in primary infections and is found in blood types?

Answer 9

IgM

Question 10

What condition is IgM associated with?

Answer 10

Low-grade lymphoma

Question 11

What disease is IgG and IgA associated with?

Answer 11

Myeloma

Question 12

What antibody isotope is of a domed shape, is present in secretions (like tears and breast milk) and is found in mucus membranes?

Answer 12

IgA

Question 13

Which anitobody isotope is the largest?

Answer 13

IgM

It’s a pentameter

Question 14

What 3 antibody isotopes are monomers?

Answer 14

IgG
IgD
IgE

Question 15

What antibody isotope is a diner, is most common in secondary infections, is present in myeloma and can cross the placenta?

Answer 15

IgG

Question 16

What antibody isotope is a monomer that is present in parasitic and fungal infections, involved in hypersensitivity and allergies?

Answer 16

IgE

Question 17

Which antibody isotope is present in severe myeloma, but we don’t actually know it’s function lol?

Answer 17

IgD