Compendium 2 Flashcards
Cell
Structural and functional unit of all living things, including humans
FUNCTIONAL CHARACTERISTCS OF CELL
- Cell matabolism and energy use
- Synthesis of molecules
- Communication
- Reproduction and inheritance
Plasma Membrane
Also known as the cell structure
FUNCTION
- encloses and supports cellular contents
- controls what goes in and out of cells
- intercellular communication (cell-to-cell)
STRUCTURE
- lipid bilayer (45-50%) – provides flexibility
- carbohydrates (4-8%)
- proteins (45-50%)
- glycocalyx (outer surface of cell membrane)
Cytoplasm
Cellular fluid membrane outside of the nucleus but within the boundaries of the plasma membrane
Nucleus
FUNCTIONS
- ‘control centre’
- deoxyribonucleic acid (DNA) – carries code for structural and functional characteristics of cell
STRUCTURE
- nuclear envelope – bilayer membrane surrounding nucleus (porous)
- nucleoplasm
- nucleolus – produces ribosomes
Ribosomes
FUNCTIONS
- site of protein synthesis
STRUCTURE
- composed of 2 subunits: large and small
- free ribosomes and membrane-bound ribosomes
Endoplasmic Reticulum
STRUCTURE
- flattened, interconnecting sacs and tubules
- RER: with ribosomes
- SER: without ribosomes
FUNCTION
- RER: synthesis and modification of proteins
- SER: site of lipid, steroid and carbohydrate synthesis
> detoxification of harmful substances
> breakdown of glycogen to glucose
Golgi Apparatus
STRUCTURE
- flattened membranous sacs, with cisternae
- secretory vesicles
FUNCTION
- modifies, packages and distributes proteins and lipids that are made in rough endoplasmic reticulum
Lysosomes
STRUCTURE
- membrane-bound vesicles that form Golgi Apparatus
FUNCTION
- ‘demolition crew’
- digestion of molecules (nucleic acids, proteins, lipids, carbohydrates, etc.) that are no longer needed
Mitochondria
STRUCTURE
- outer membrane
- intermediate space
- inner membrane
- matrix
- change shape continuously
- own genetic material – reproduce itself
FUNCTION
- ‘power plant of cell’
- ATP (adenosine triphosphate) production and supply
> unit of currency for energy
Centrioles (+ centrosome)
STRUCTURE
- barrel-shaped, orientated at right angles
- wall composed of microtubules
- found in centrosome
FUNCTION
- cell division
Cilia
STRUCTURE
- whip-like cellular extensions
- project from outer surfaces of cells
FUNCTIONS
- movement of substances across surface of cells
> lining of respiratory tract - mucus out of lungs
> fallopian tubes - moves egg
Flagella
STRUCTURE
- longer than cilia
- sperm cells only
- moves the cell
FUNCTION
- motility
Microvilli
STRUCTURE
- extension of plasma membrane
- 1/10 - 1/20 size of cilia
- non-motile
FUNCTION
- increases cell’s surface area
> absorptive cells of intestine or kidney tubules
Histology
study of tissues
Histology
PREPARATION OF TISSUE
- removal of tissue from the body via biopsy or autopsy
- fixation of tissue
- embedding of the tissue
- slicing of the tissue and mounting tissue on a slide
- staining and viewing using a microscope
Histology
HAEMATOXYLIN AND EOSIN
(H + E)
Nuclei are stained purple (haematoxylin) whereas other cell structures, cytoplasm, are stained pink (Eosin)
Histology
POINTS TO CONSIDER
- plane the tissue has been cut in
2. magnification of image
Primary Tissues
All organs in the body contain all four primary tissue types
- epithelial tissues (covers)
- connective tissues (support)
- muscle tissues (movement)
- nervous tissues (control)
Epithelial Tissue
CHARACTERISTICS OF EPITHELIAL TISSUE
Epithelium
Covers and protects - covering and lining epithelium - glandular epithelium Distinct cell surfaces - free surface - lateral surface - basal surface (basement membrane) Avascular but innervated Ability to regenerate
Epithelial Cells
SIMPLE SQUAMOUS
Simple layer of flattened cells with sparse cytoplasm
FUNCTIONS
- diffusion, filtration and some secretion
LOCATIONS
- alveoli, kidney glomeruli, serous membranes of pleura, pericardium and peritoneum
Epithelial Cells
SIMPLE CUBOIDAL
Single later of cubed-shaped cells. Some of these cells have microvilli or cilia
FUNCTIONS
- absorption, secretion and movement
LOCATIONS
- kidney tubules and terminal bronchioles
Epithelial Cells
SIMPLE COLUMNAR
Single layer of column-shaped or tall cells with round to oval nuclei. Some cells have cilia
FUNCTIONS
- absorption, secretion and movement
LOCATIONS
- intestines, stomach, fallopian tubes and lings
Epithelial Cells
TRANSITIONAL
Resembles stratified squamous and stratified cuboidal cells depending on its state
FUNCTIONS
- accomodate changes in fluid volume of the organs
LOCATION
- urinary bladder, ureter, and upper part of urethra
Epithelial Cells
STRATIFIED SQUAMOUS
Basal cells are cuboidal or columnar and become progressively flatter as you move to the surface. Several layers of cells (Keratinized, non-keratinized)
FUNCTIONS
- protection against abrasion and loss of water
LOCATIONS
- keratinized: sole of feet, palm
- non-keratinized: mouth, oesophagus, anus, vagina