Comparison of Fungal Diseases Flashcards
Histoplasmosis: source
Nitrogenous soil-Bird/bat
pewp
Coccidiodomycosis: Geography
American southwest
Coccidiodomycosis: Yeast or Mold dimorphic
Dimorphic- Not temp. dependent
Host - Spherules and endospores
Candidiadsis (opportunistic: yeast or Mold dimorphic
Dimorphic Exception - yeast in environment- hyphal form in vivo tissues
Cyrptococcosis (opportunistic): Yeast or Mold Dimorphic
Environment: yeast- Polysaccharide capsule in host (anti-phagocytic)
Cyrptococcosis: Organ system involved
Asymptomatic in lungs, meningitis severe
Apergillosis (opportunistic): Yeast or Mold Dimorphic
Filamentous fungi- mold conidia are inhaled and germinate into hyphae
Angioinvasive Fungus- Hyphae invade blood vessels
Apergillosis Diagnosis
Grows on agar but contamination is common- tissue biopsy can confirm tissue invasion
Dermatophytosis (opportunistic): Organ system involved?
Restricted to Kertinized tissues (skin, hair, and nails)
Dermatophytosis: Yeast & Mold Dimorphic
Mold exclusively
Sporotrichosis (Subcutanous) also known as?
Rose Pickers Disease
Sporotrichosis Source?
Soil, moss, ROSE THORNS, decaying wood etc
Fungi Cause disease by inducing an _____ or through _____ or destruction of tissues (some produce _____)
fungi
inflammatory response
direct invasion
toxins
All systemic infections of ______ are life-threating and require therapy
candida
Treatment for fungal infection:
Polyenes: Amphotericin B
Azoles: Itraconazole