communication, homeostasis and energy Flashcards
what is the central nervous system composed of?
brain
spinal cord
what does the central nervous system contain?
relay neurons
what is the peripheral nervous system composed of?
cranial nerves
spinal nerves
peripheral nerves
what does the peripheral nervous system contain?
sensory neurons
motor neurons
where is the cell body located in a motor neuron?
on the end of the axon
on the left side
what is the cell body of a neuron called?
soma
what is the sequence of the nervous system?
- stimulus
- receptor cells
- sensory neurons
- CNS (relay neurons)
- motor neuron
- effector
- response
what is the peripheral nervous system divided into?
sensory division
motor division
what is the sensory division made up of?
sensory neurons
what does the sensory division do?
signals from receptors to CNS
what is the motor division made up of?
motor neurons
what does the motor division do?
signals from CNS to receptors
what is the motor division divided into?
autonomic nervous system
somatic nervous sytem
what does the autonomic nervous system do?
controls involuntary responses
what does the somatic nervous system do?
controls voluntary movement
what is the autonomic nervous system divided into?
sympathetic division
parasympathetic division
what does the sympathetic division do?
mobilises body systems
‘fight or flight’ responses
what does the parasympathetic division do?
conserves energy
‘rest and digest’ responses
what is the stimulus pathway?
- stimulus
- receptor
- sensory neuron
what are the types of stimulus?
physical (temp/press/light)
chemical
what is a biological transducer?
receptors
converts stimuli into electrical signals
what is mechanical pressure?
pressure caused by a physical force
what is the pacinian corpuscle?
receptor that responds to mechanical pressure
transduce mechanical energy of the stimulus into a generator potential
what are photoreceptors?
respond to light
found in the eye
what are chemoreceptors?
respond to chemicals
found in the nose
what are mechanoreceptors?
respond to mechanical strain/stretching
found in the skin
what are baroreceptors?
respond to blood pressure
found in blood vessels and the heart
what are osmoreceptors?
respond to bodily fluids
found in the hypothalamus and cartoid artery
what is action potential?
a nerve impulse which causes depolarisation of the nerve cells membrane by ions moving across
what are the 3 main stages in creating action potential?
depolarisation
repolarization
refractory period
what gets pumped out in the sodium-potassium pump?
3 sodium ions (NA+)
what gets pumped in the sodium-potassium pump?
2 potassium ions (K+)
what are mylinated nerve fibres?
made of schwann cells which wrap around the axon
have high lipid content to create insulated layer
what helps cause faster nerve impulses?
wider diameter of neurons
myleniated diameters
what is multiple sclerosis?
autoimmune condition
affects around 100,000 people in the UK
mistakenly attacks the myelin sheath in the brain and spinal cord
unknown triggers (genetic + environmental factors)
how does multiple sclerosis slow down nerve impulses?
due to breaking down the mylin
can affect axons so interrupts signals passing
where is the pacinian corpuscle found?
deep within the skin
in the dermis layer
(in skin of fingers, soles of feet, tendons + ligaments)
whats the structure of the pancinian corpuscle?
made of many layers of membrane around the end of the neurone seperated by a gel
contains a blood capillary, capsule and sensory neuron
what does the gel between the layers in a pacinian corpuscle contain?
positively charged sodium ions (NA+)
how is action potential formed in sensory neuron?
- normal resting state - too narrow to allow sodium to move through
- pressure applied - change shape so neuron membrane stretch
- membrane stretches - sodium channels widen, NA+ diffuses in
- depolarises membrane - results in generator potential
- action potential is generated
what is depolarisation?
an electrical change within a neuron from a (relatively) negative charge to a positive charge
what happens in depolarisation?
Na channels open
influx of sodium in
membrane to become more positive
what is repolarisation?
an electrical change within a neuron from a (relatively) positive charge to a negative charge
what happens in repolarisation?
(after an influx of Na+) potassium channels open
as K+ is more concentrated inside the neuron, it moves out
causes the inside to become relatively negative again
what is the refractory period?
period in which neuron is unresponsive to stimulation (ion distribution is being restored)
what happens in the refractory period?
the membrane is hyperpolarised
voltage dependent potassium channels now close
K+ diffuses back into the axon
sodium-potassium pump restores the resting potential
what is the course of events (+what happens) in nerve impulses?
- resting potential (Na+/K+ pump)
- depolarisation (voltage gated Na+ channel opens)
- repolarisation (voltage gated K+ channel opens)
- resting potential (Na+/K+ pump)
what is saltatory conduction?
increases nerve transmission
Na+ inflow at node generates action potential
gives impression that influxes jump to node of Ranveirs
whats a synaptic cleft?
tiny gap between cells at the synapse
what does the synaptic knob contain?
synaptic vesicles filled with neurotransmitters
how does the response not keep happening after action potential occurs?
removed from the cleft
taken back into the presynaptic neurone
broken down by enzymes
how do neurotransmitters transmit nerve impulses between neurones?
- an action potential triggers calcium influx
- calcium influx causes neurotransmitter release
- the neurotransmitter triggers an action potential in the postsynaptic neurone
what is an excitatory synapse?
neurotransmitters depolarise the postsynaptic membrane and make it fire an action potential if the threshold is reached
what is an inhibitory synapse?
when neurotransmitters bind to receptors on postsynaptic membrane they hyperpolarise the membrane (more negative) which prevents an action potential from being fired
what is synaptic divergence?
when one neuron connects to many neurons information can be dispersed to different parts of the body
what is synaptic convergence?
when many neurons connect to one neurone information can be amplified
what is spatial summation?
signals from multiple stimuli are coordinated into a signal response
small amount of neurotransmitter released from each neuron can be enough altogether to reach the threshold
what is temporal summation?
where two (or more) nerve impulses arrive in quick succession from the same presynaptic neuron
makes an action potential more likely since more neurotransmitter is released into the synaptic cleft
how can glands be stimulated?
by a change in concentration of a specific substance (sometimes another hormone)
by electrical impulses
how do hormones travel?
in the bloodstream
in the circulatory system
what is a target cell?
where there is specific receptors found on the membranes
what’s the order of the hormonal system sending chemicals?
- stimulus
- receptors
- hormone
- effectors
- response
why is a hormone a first messenger?
it carries the chemical message the first part of the way
(from endocrine gland to receptor on the target cells)
what happens when a hormone binds to its receptor?
it activates an enzyme in the cell membrane
what happens once the enzyme is activated in the cell membrane?
it catalyzes the production of a signaling molecule
what is a signalling molecule?
it signals to other parts of the cell to change how the cell works
why is a signalling molecule a second messenger?
it carries the chemical message the second part of the way
(from receptor to other parts of the cell)
what do second messengers do?
activate a cascade inside the cell
example: adrenaline
(trigger second messenger pathway)
- adrenaline as first messenger
- binds to specific receptors in the cell membranes
- activates the enzyme adenylyl cyclase
- catalyses production of second messenger cyclic AMP (cAMP) from ATP
- cAMP activates a cascade to make more glucose available
what are the parts of the adrenal glands?
outer part = cortex
inner part = medulla