biodiversity, evolution and disease Flashcards
active immunity
resistance in an organism that has developed through the production of specific antibodies in response to a pathogen
it provides long-lasting immunity as memory cells are produced
agglutinins
chemicals that cause pathogens to aggregate together, aiding phagocytosis
antibodies can act as agglutinins
antibiotic
a chemical or compound produced by a living organism that kills or prevents the growth of bacteria
antibiotic-resistant bacteria
bacteria that mutate to become resistant to an antibiotic, survive and reproduce very rapidly, passing on their antibiotic resistance
antibodies
immunoglobulins produced by B-lymphocytes in response to a specific antigen, triggering an immune response
antigen
a chemical present on the surface of a cell that induces an immune response
antigen-presenting cell
a macrophage that displays forgein antigens
anti-toxins
chemicals produced by white blood cells that neutralise toxins released by pathogens
artificial active immunity
the production of antibodies by the immune system following the expose to a weakened, attenuated or dead pathogen
artificial immunity example
vaccination
artificial passive immunity
the immunity acquired from the administration of specific antibodies from another organism
athlete’s foot
a form of ringworm in humans that effects the feet, resulting in cracking and scaling of the skin
autoimmune disease
a condition in which the immune system attacks and destroys healthy body tissue
bacteria
prokaryotic cells that have cell walls but lack organelles
some are pathogenic (produce toxins that damage host cells)
bacterial meningitis
a severe form of meningitis caused by bacterial infection of the meninges
complications of bacterial meningitis include septicaemia (a symptom of this is a rash of purple discolouration that does not fade when a glass is pressed against it)
b effector cells
a type of b lymphocyte that divides to form plasma cells
black sigatoka
a fungal disease in tomatoes cause by mycosphaerella fijiensis
the hyphae of which penetrate and digest host leaf cells - turning them black
b lymphocytes
lymphocytes that mature in the bone marrow
three main types: plasma cells, b effector cells and b memory cells
b memory cells
b lymphocytes that provide immunological memory
callose
a plant polysaccharide
contains b-1,3 and b-1,6 linkages between glucose molecules
deposited between the cell walls and cell membrane in cells adjacent to infected cells, serving as a defence agaisnt pathogens
also found in the cells walla of infected cells and the plasmodesmata between infected cells
chitinases
enzymes that degrade chitin in fungal cells walls
clonal expansion
the mass proliferation of specific antibody-producing cells
clonal selection
the identification of an antibody-producing cell with complementary receptors to the shape of a specific antigen
clostridium difficile
a type of bacteria found in the gut of some people
its resistant to most antibiotics
communicable disease
a disease that is caused by a pathogen and transmitted directly between organisms
cytokines
cell signalling molecules produced by mast cells in damaged tissue
they attract white blood cells to the site of damage
direct transmission
the transfer of a pathogen directly from one organism to another
this can occur via direct contact, ingestion or the sharing of contaminated needles
epidemic
a rapid rise in the incidence of a communicable disease at a local or national level
expulsive reflexes
coughs or sneezes intiated upon irritation of the respiratory tract
they remove microorganism-containing mucus from the gaseous exchange system
fungi
eukaryotic, often multicellular organisms that may cause disease
they digest and destroy cells, and produce spores that can spread rapidly between organisms
glucanases
enzymes produced by plants that decompose glucans, polysaccharides found in oomycete cell walls
histamine
a chemical produced by mass cells in damaged tissue
makes blood vessels dilate and causes their walls to become leakier
human immunodeficiency virus (HIV)
infectious virus that destroys T helper cells, weaking the immune system of the body
makes sufferers more susceptible to infections and can lead to AIDS
indirect transmission
the transfer of a pathogen indirectly between organisms via fomites, vectors, droplet infection or soil contamination
inflammation
a localised response of vascular tissue to pathogens, damage or irritants
its characterised by pain, redness, heat and swelling
influenza
a common viral infection caused by the family of viruses orthomyxoviridae
destroys ciliated epithelial cells in the gaseous exchange system, exposing the airways to secondary infection
interleukins
cytokines produced by T helper cells that stimulate B cells
lymphocytes
white blood cells that contribute to the specific immune response
lysosome
a membrane bound organelle that contains hydrolytic enzymes
malaria
a disease caused by the protocista plasmodium that lives within two hosts (mosquitoes and humans)
causes recurrent episodes of fever and can be fatal
mast cells
specialised cells in connective tissue that are important in the inflammatory response, releasing histamines and cytokines
MRSA
a type of bacteria that is resistant to the antibiotic methicillin
mucous membranes
the membranes lining body cavities that secrete a sticky mucus
natural active immunity
the production of antibodies by the immune system following infection
natural passive immunity
the immunity acquired by an infant mammal when antibodies are transferred through the placenta and the colostrum from the mother
non-specific defences
defenses that are always present and are the same for all organisms
opsonins
chemicals that bind to and tag forgein cells, making them easily recognisable to phagocytes
passive immunity
resistance in an organism acquired via the transfer of antibodies
it provides short term immunity as no memory cells are produced
pathogen
a disease-causing microorganism
includes bacteria, viruses, fungi and protocista
penicillin
discovered by alexander flemming
the first conventional, effective and safe antibiotic derived from the mould penicillium chrysogenum
personal medicine
form of medical care that enables doctors to provide healthcare that is customised to an individual’s genotype
phagocytes
specialised white blood cells that engulf and destroy pathogens
two types: neutrophils and macrophages