Commonly Used GI medications in Small Animal General Practice

Question 1

For famotidine:
1. State the drug class/MOA
2. Route
3. Common indications

Answer 1

1. H2 receptor anatagonist
2. Any route
3. GI cases –> reduce acid production

Question 2

For lactulose:
1. State the drug class/MOA
2. Route
3. Common indications

Answer 2

1. Laxative and ammonia reducer
2. PO
3. Stool softner + hepatic encephalopathy

Question 3

For maropitant:
1. State the drug class/MOA
2. Route
3. Common indications
4. Special considerations

Answer 3

1. Antiemetic + NK1 receptor anatagonist –> blocks substance P
2. IV/SC/PO
3. Vomiting
4. Cautious use in cases of FB

Question 4

For metoclopramide:
1. State the drug class/MOA
2. Route
4. Common indications
5. Special considerations

Answer 4

1. GI prokinetic + antiemetic agent
2. IV/SC/IM and PO
3. gastic motility disorders + vomiting cases + post-surgical ileus
4. Avoid in GI obstruction, perforation and/or haemorrhage cases

Question 5

For metronidazole:
1.State the drug class
2. MOA
3. Route
4. Common indications
5. Special considerations

Answer 5

1. Nitroimidazole antibiotic + antiparasitic agent
2. PO/IV
3. Common indications: Giardia, protozoal, IBD, Non-specific diarrhoea disorders + colitis cases
4. Neurotoxicosis

Question 6

For mirtazapine:
1. State the drug class/MOA
3. Route
4. Common indications
5. Special considerations

Answer 6

1. Tetracyclic antidepressant + 5HT3 antagonist
2. PO
3. appetite stimulant w/antimemetic
4. Avoid use w/ other antidepressants e.g. SSRI’s

Question 7

For omeprazole:
1. State the drug class/MOA
3. Route
4. Common indications
5. Special considerations

Answer 7

1. Proton pump inhibitor
2. PO and IV
3. GI disorders -> reduce gastric acid secretion

Question 8

For ondansetron:
1. State the drug class/MOA
3. Route
4. Common indications
5. Special considerations

Answer 8

1. 5HT3 receptor antagonist
2. IV and PO
3. Antiemetic in vomiting cases
4. Side effects of chemotherapy

Question 9

What is the function of sucrulfate?

Answer 9

Gastroprotectant - given PO - protects against GI ulceration