Common Skin Disorders Flashcards
Define Acne Vulgaris
Inflammation of pilosebaceous units of certain body parts
Clinical Presentation of Acne Vulgaris
Lesions on the skin
Pain in lesions Lesions include: comedones, papulopustules, nodules, and cysts
4 Factors Involved in Acne Vulgaris
Follicular hyperkeratinization
Increased sebum production
P. acnes within the follicle
Inflammation
Acne Vulgaris Grade I
Minimal blackheads
Few papules
Acne Vulgaris Grade II
10+ blackheads, papules, & pustules
Redness
Inflammation
Acne Vulgaris Grade III
15-20+ blackheads, papules, & pustules
Redness
Inflammation
Acne Vulgaris Grade IV
Severe case
Extreme amount of pustules
Extreme edema
Diagnosis of Acne Vulgaris
Clinical
Female patients with dysmenorrhea or hirsutism: total/free testosterone, DHEA-S, LH, FSH
Treatment of Acne Vulgaris
OTC 1st line: Topical retinoids 2nd line: Topical antibiotics Oral therapies Oral isotretinoin
OTC Treatment for Acne Vulgaris
Benzoyl peroxide
Salicylic acid
Topical Retinoid Treatment for Acne Vulgaris
1st line
Adapalene (Differin)
Tretinoin (Retin-A)
Tazarotene (Tazorac)
Topical Antibiotic Treatment for Acne Vulgaris
2nd line
Clindamycin
Erythromycin
Oral Therapies for Acne Vulgaris
Doxycycline
Minocycline (Minocin)
Oral Isotretinoin Treatment for Acne Vulgaris
For severe treatment failure
Register in iPLEDGE program
Teratogenic
Monitor: CBC, LFTs, & transaminases
Define Rosacea
Chronic acneform disorder of facial pilosebaceous units
Increased reactivity of capillaries to heat
Exacerbating Factors of Rosacea
Hot liquids Spicy foods Alcohol Exposure to sun & heat Cold Exercise Emotions Menopausal flushing
Clinical Presentation of Rosacea
Redness to the cheeks, nose, & chin
Burning or stinging with episodes
4 Types of Rosacea
Erythematotelangiectatic rosacea
Papulopustular rosacea
Phymatous rosacea
Ocular rosacea
Treatment of Rosacea
Minimize precipitating factors 1st line mild to moderate: topical antibiotics Moderate to severe: systemic antibiotics Laser treatment for telangiectasia Pulsed-light therapy for erythema Cleansers Photodynamic therapy
Topical Antibiotics for Rosacea
Azalea Acid Metronidazole Erythromycin Clindamycin Brimonidine
Systemic Antibiotics for Rosacea
Tetracycline
Doxycycline/Minocycline
Erythromycin
Complications of Rosacea
Eye involvement
Gram negative folliculitis
Permanent telangiectasias
Rhinophyma
Define Rhinophyma
Soft tissue hypertrophy related to vasodilation
Define Folliculitis
Infection of the hair follicles
Common Bugs of Folliculitis
Staphylococcus aureus
Pseudomonas
Yeast: exception
Symptoms of Folliculitis
Red pimples with a hair in the center
May itch or burn
Treatment of Folliculitis
Warm compresses 3 times daily
Avoid shaving in areas
Topical antibiotics: Mupirocin (Bactroban)
Define Pseudobarbae Folliculitis
Razor bumps
How does pseudobarbae folliculitis occur?
When free ends of tightly coiled hairs reenter skin & cause a FB inflammatory response
Treatment of Pseudobarbae Folliculitis
Stop shaving Laser hair removal Adjunctive medical therapy Warm compresses Remove hair with tweezers
Adjunctive Medical Therapy for Pseudobarbae Folliculitis
Topical retinoids
Low potency corticosteroids
Topical antimicrobials
Define Furuncles (Boils)
Skin abscesses caused by staphylococcal infection of a hair follicle
Define Carbuncles
Cluster of furuncles
Common Areas for Furuncles/Carbuncles
Buttocks Axillae Neck Face Waist
Predisposing Factors for Furuncles/Carbuncles
DM Malnutrition Obesity Hematologic disorders Hot, humid climates Occlusion of anatomy
Treatment of Furuncles/Carbuncles
Hot compresses
I&D
Packing may be necessary
Systemic antibiotics
Systemic Antibiotics for Furuncles/Carbuncles
Bactrim
Clindamycin
Cephalexin (Keflex)
Common Bugs for Impetigo
Staph
Strep
Describe Impetigo
Red lesions that can break open, ooze
Develop a yellow-brown crust (honey colored)
Where do impetigo sores usually appear?
Mouth
Nose
Treatment of Impetigo
2% Bactroban ointment or cream
Severe: oral clindamycin or erythromycin
Clinical Characteristics of Junctional Nevi
Light brown to nearly black
Usually flat but may be slightly elevated
1-10 mm
Clinical Characteristics of Compound Nevi
Light brown to dark brown
May be slightly or considerably elevated
3-6mm
Clinical Characteristics of Intradermal Nevi
Flesh-colored to brown
May be smooth, hairy, or warty
Elevated
3-6 mm
Clinical Characteristics of Halo Nevi
Any type of mole surrounded by a 2-6 mm ring of depigmented skin
Clinical Characteristics of Blue Nevi
Bluish gray
Usually flat but may be slightly elevated
2-4 mm
ABC’s of Biopsies of Moles
A: asymmetry B: borders C: color D: diameter E: elevated, evolution
Treatment of Moles
Removed with shaving or excision
Describe Solar Lentigos
Flat, brown areas of skin that can be up to one inch in diameter
Benign & painless
Treatment of Solar Lentigo
Cryotherapy Tretinoin cream Hydroquinone cream Triple combination cream: fluocinolone acetonide, hydroquinone, tretinoin Bleaching solutions & chemical peels
Describe Seborrheic Keratosis
Common, multiple, benign skin lesions commonly found on the torso
Presentation of Seborrheic Keratosis
Well-circumscribed gray-brown-to-black plaques with a “stuck on” appearance
Warty
Often scaly
Hyperpigmented lesion
Treatment for Seborrheic Keratosis
Cryotherapy Curettage & Cautery Laser surgery Shave biopsy Send suspicious looking lesions for pathology
Describe Actinic Keratosis (AKs)
Rough, dry, scaly patch or growth that forms on the skin
Symptoms of Actinic Keratosis (AKs)
Rough feeling patch on skin
Rough patch that feels painful when rubbed
Itching or burning
Lips feel constantly dry
Causes of Actinic Keratosis
Sun exposure
Tanning beds
Treatment of Non-hypertropic AKs
Liquid nitrogen cryotherapy
Treatment of Hypertrophic AKs
Surgical curettage: send to path
Treatment of Multiple AKs
Topical 5-FU (Efudex) or imiquimod (Aldara)
Describe Melasma (Pregnancy Mask)
Tan or brown patches on the cheeks, nose, forehead, & chin
Triggers of Melasma (Pregnancy Mask)
Sun exposure
Change in hormones
Cosmetics
Diagnosis of Melasma (Pregnancy Mask)
Clinical
Biopsy
Treatment of Melasma
Self-limiting
1st: hydroquinone
2nd: tretinion & steroids
Micro-dermabrasions
Different Types of Tinea
Capitis Corporis Pedis Cruris Versicolor
Define Tinea Capitis
Round patches of dry scale, alopecia, or both
Diagnosis of Tinea Capitis
Clinical
Wet mount
Woods lamp
Treatment of Tinea Capitis
Griseofulvin (kids)
Terbinafine (adults)
Selenium sulfide shampoo
Define Tinea Corporis
Pink-to-red O-shaped patches & plaques
Treatment of Tinea Corporis
Mild to moderate: imidazole
Extensive or resistant: oral itraconazole
4 Forms of Tinea Pedis
Chronic hyperkeratotic
Chronic intertriginous
Acute ulcerative
Vesiculobullous
Distribution of Chronic Hyperkeratotic Tinea Pedis
In a moccasin distribution
Define Chronic Intertriginous Tinea Pedis
Lateral 3 toes most common
Describe Acute Ulcerative
Toes 4 & 5 and into the arch
Describe Vesiculobullous Tinea Pedis
Vessels/blisters on the soles
Treatment of Tinea Pedis
Itraconazole (antifungal)
Miconazole powder
Burrow solution soaks
Risk Factors for Tinea Cruris
Warm weather
Wet restrictive clothing
Obesity
Describe Tinea Cruris
Pruritic ringed lesions that extend from crural fold over adjacent upper thigh
Treatment of Tinea Cruris
Clotrimazole
Ketoconazole
Describe Tinea Versicolor
Multiple asymptomatic scaly patches varying in color
Risk Factors for Tinea Versicolor
Heat & humidity
Pregnancy
DM
Undernutrition
Presentation of Tinea Versicolor
Asymptomatic
Appearance of multiple tan, brown, salmon, pink, or white scaling patches
Diagnosis of Tinea Versicolor
KOH wet mount
Woods lamp
Treatment of Tinea Versicolor
Topical antifungals
Oral antifungals
Topical Anti-fungals for Treatment of Tinea Versicolor
Selenium sulfide shampoo
Ketoconazole
Oral Anti-fungals for Treatment of Tinea Versicolor
Ketoconazole
Fluconazole
Signs/Symptoms of Tinea Overall
Pruritis
Annular, scaly plaques with raised erythematous edges
Central Clearing
Labs for Tinea Overall
KOH wet mount
Wood’s lamp
Culture
What is found with a wood’s lamp for tinea?
Brilliant silver-blue fluorescence of infected hair
Presentation of Fifth’s Disease
Bright red raised rash on the face, then arms, legs, and trunk
Flu-like symptoms
Treatment for Fifth’s Disease
NSAIDs
Complications of Fifth’s Disease
Pregnancy: baby severe anemia & miscarriage or stillbirth
Presentation of Hand-Foot-Mouth Disease
Fever
Painful mouth sores
Non-pruritic rash with blisters
How does hand-foot-mouth disease spread?
Coughing
Sneezing
Treatment for Hand-Foot-Mouth Disease
Ibuprofen or acetaminophen
Fluids
Scarlatina (Scarlet Fever) Rash
Fine, red, & rough-textured
12-48 hours after the fever (blanches with pressure)
Starts on the chest, armpits, & behind the ears
Spares the face
Swollen red tongue (strawberry tongue)
If Scarlatina (scarlet fever) is left untreated, what disease may occur?
Rheumatic fever
Glomerulonephritis
Meningitis
Pneumonia
Treatment of Scarlatina (Scarlet Fever)
1st: Penicillin
2nd: first-generation cephalosporin
Penicillin allergy: clindamycin, erythromycin
Symptoms of Roseola
Respiratory illness
High fever for 3-5 days
Rash: small, pink, flat, or slightly raised bumps on the trunk (then extremities)
Treatment of Roseola
Supportive
Describe Heat Rash (Miliaria)
Small red or pink pimples
Location of Heat Rash (Miliaria)
Infants head, neck, shoulders Groin Underneath the breasts Creases of elbow Armpits
Treatment of Heat Rash (Miliaria)
Keep skin cool & dry Cool down Dry off Reduce friction Treat fever
Define Skin Tag
Small flap of fresh-colored or slightly darker tissue that hangs off the skin by a connecting stalk
Common Areas for Skin Tags
Neck Chest Back Armpits Under the breasts In the groin area
Treatment for Skin Tags
Removal by cutting or cryotherapy
Define Corns
Central hard core that is painful if lesion is pressed
Prevention of Corns & Callouses
Eliminate Friction & pressure via:
Shoes that fit correctly & distribute pressure evenly
Softer shoe material
Treatment of Corns & Callouses
Paring down of hyperkeratotic lesions with a scalpel
Keratolytic agents can be used intermittently
Pumice stone