Common Oral Lesions-Dr. Hasan Flashcards

1
Q

What are you most likely going to see in your practice?

A
  • Aphthous Ulcer
  • Traumatic Lesions
    • ulcerative
    • fibroma
  • Lichen Planus/Lichenoid Reaction
  • Denture related oral lesion
  • Viral Lesions
  • Geographic Tongue
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2
Q

What will you occasionally see in your practice?

A
  • MMP
  • Pemphigus Vulgaris
  • Erythema Multiforme
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3
Q

What are the 2 major categories of oral lesions

A
  • Infectious Etiology
  • Non-infectious Etiology
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4
Q

What oral lesions fall under infectious etiology?

A
  • Oropharyngeal Candida
  • Herpes Simplex
  • Herpes Zoster
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5
Q

What oral lesions fall under Non-Infectious Etiology

A
  • Painful Traumatic Lesions
  • Traumatic Fibroma
  • Aphthous Stomatitis
  • Geographic Tongue
  • Lichen Planus/Lichenoid Reaction
  • Mucous Membrane Pemphigoid
  • Pemphigus
  • Cancer
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6
Q

Oropharyngeal Candida consists of:

A
  • Pseudomembranous Candidiasis
  • Erythematous (Atrophic) Candidiasis
  • Chronic Hyperplastic Candidiasis
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7
Q

Oropharyngeal Candida associated conditions

A
  • Angular Cheilitis
  • Central Papillary Atrophy
    • (median Rhomboid glossitis)
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8
Q

Pseudomembranous Candidiasis

A
  • aka Thrush
  • Most common form of candidiasis
  • opportunistic infection
  • Common locations:
    • buccal mucosa
    • palate
    • tongue
  • Cause fungal laryngitis
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9
Q

Erythematous Candidiasis

A
  • Red areas
  • Presentation:
    • burning
    • stinging
    • itching
    • altered taste
  • Locations
    • palate
    • dorsal of tongue
  • Associated with:
    • dryness
    • compounded by use of dentures, antibiotics, or steroids
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10
Q

DAS

A
  • Denture Associated Stomatitis
  • caused by contaminated dentures
  • Most susceptible:
    • elderly
    • immunocompromised
  • Diagnosed by:
    • swab & grow fungus on S. Agar medium
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11
Q

Chronic Hyperplastic Candidiasis (CHC)

A
  • old name- candidal leukoplakia
  • oral candidiasis variant
  • Caused by Candida albicans
  • Asymptomatic
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12
Q

Angular Cheilitis

A
  • Aka:
    • Perleche
    • Angular Stomatitis
    • Cheilosis
  • Diagnosed by presence of inflammation and fissuring of oral commisures
  • Burning sensation or tender corners of mouth
  • may limit range of motion of the mouth
  • impaired eating
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13
Q

Central Papillary Atrophy

A
  • AKA Median Rhomboid Glossitis
  • tongue missing filiform papilla
  • Chronic Fungal (Candidiasis) infection
  • Kissing lesions
    • sometimes
    • develops on the palate
  • Common in immunosuppressed
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14
Q

Herpes Simplex Virus

A
  • aka herpes
  • 2 types:
    • Herpes Simplex virus type 1 (HSV-1)
    • Herpes Simplex virus type 2 (HSV-2)
  • Symptoms=most contagious
    • painful blisters or ulcers
    • tingling, itching, or burning before blisters appear
    • asymptomatic viral shedding=still contagious
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14
Q

compare and contrast HSV-1 and HSV-2

A
  • HSV-1
    • transmission: Oral to oral contact
    • cause:
      • oral herpes
        • symptoms-cold sores
      • genital herpes
  • HSV-2:
    • sexually transmitted
    • causes:
      • genital herpes
    • increases the risk of acquiring and transmitting HIV infection
  • Both:
    • lifelong infections
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15
Q

How can children get infected by herpes simplex virus?

A
  • infected adult
    • kiss
    • eating from same utensil
    • sharing a towel
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16
Q

How long will it take for herpes to show up after contact with an infected person?

A
  • 2-20 days
17
Q

What is Herpes Prodrome?

A
  • Fever
  • Malaise
  • GI symptoms
  • LAD
  • headache
18
Q

Where do most blisters appear for Herpese Simplex virus?

A
  • Lips
  • around mouth
  • Sometimes
    • face
    • tongue
19
Q

Herpes Simplex Virus: Differential Diagnosis

A
  • Varicella Zoster Virus
20
Q

What causes Herpes Simplex virus to recurr?

A
  • Cold
  • Stress
  • Sunlight
  • Trauma
  • Immunosuppresion
  • RHL (recurrent Herpes Labialis)
    • cold sore
    • fever blister-most common form
21
Q

Varicella Zoster Virus (VZV)

A
  • aka shingles, Herpes Zoster
  • Primary infection=varicella (chickenpox)
    • Recurrent infection= herpes zoster (shingles)
  • dormant/latent in Dorsal root ganglia
  • Causes Herpes zoster
    • painful, maculo-papular rash
    • appears 1st on head
    • most concentrated on trunk
22
Q

Varicella Zoster Virus: Clinical Features

A
  • More severe in HIV patients
  • Intraoral lesions
    • more severe
    • involve bone=tooth loss
  • Mild prodrome: 1-2 days
23
Q

How is VZV transmitted?

A

Respiratory transmission

24
Q

What is the incubation period for Varicella Zoster Virus?

A
  • 14-16 days
    • range 10-21 days
25
Q

Traumatic Lesions

A
  • More prevalent in patients with oral dryness
    • can be seen w/normal salivary flow
26
Q

Aphthous Stomatitis

A
  • unclear etiology
    • factor=altered immune response
  • Any age
  • Herpetiform=not common
  • minor lesion: ≤ 0.5cm
  • Major lesion: ≤ 3.0cm
27
Q

Aphthous Stomatitis: Differential Diagnosis

A
  • Bahcets disease
  • Crohns disease
  • Contact Dermatitis
  • Herpes simplex
  • Lichen planus
28
Q

What causes Geographic tongue?

A
  • unknown
    • possible factors
      • emotional stress
      • psychological factors
      • habits
      • allergies
      • diabetes
      • hormona disturbances
29
Q

Geographic tongue

A
  • oral form of psoriasis
  • any age
  • varies in color, shape, and size
30
Q

Lichen Planus

A
  • autoimmune
  • occurs in 1-2% adults
    • usually middle aged females
  • Involves:
    • vagina
    • Skin (10-15%)
  • Biopsy solitary white plaque
    • leukoplaque & erythroleukoplakia misdiagnosed as LP
31
Q

What are the different types of LP

A
  • Reticular
  • Erythematous/Erosive
  • ulcerative
32
Q

Reticular Lichen Planus

A
  • White striations (webbed)
  • Located on:
    • buccal mucosa
    • labial mucosa
    • ventral & dorsal tongue
    • gingiva
  • Asymptomatic usually
  • Tx: if symptomatic
    • if no improvement=biopsy
    • see patient 1 time per year
33
Q

Erythematous/Erosive Lichen Planus

A
  • Red areas
  • raw appearance
  • Located on
    • gingiva
  • painful
  • requires Tx
34
Q

Ulcerative Lichen Planus

A
  • Any surface
    • tongue=causes atrophy of taste buds
  • painful
  • severe case=hx of weight loss
35
Q

Lichen Planus: Differential Diagnosis

A
  • Epithelial Dysplasia
  • MMP
  • Chronic GVHD
  • Chronic Ulcerative Stomatitis
36
Q

Painful Traumatic Lesions

A
  • More prevalent w/oral dryness
    • seen w/normal salivary flow
37
Q

Mucous Membrane Pemphigoid (MMP)

A
  • autoimmune
  • Middle Aged females
  • Painful bleeding gums when brushing
  • Hx of oral and skin blisters
  • Desquamative gingivitis
    • bright red, tender gingiva
  • Limited to oral cavity mostly
    • ocular lesions-refer
38
Q

MMP Differential Diagnosis

A
  • Lichen Planus
  • Aphthous ulcer
  • Pemphigus
39
Q

Pemphigus

A
  • Middle aged and older patients
    • jewish decent
  • Located on:
    • palate
  • Painful ulcers
    • shallow erosion
    • involves esophagus
  • oral lesion might be only manifestation
  • Positive Nikolsky sign
  • associated w/desquamative gingivitis
40
Q

Pemphigus Differential Diagnosis

A
  • Pemphigoid
  • Ulcerative LP
  • Erythema Multiforme