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PSA revision > Common drug SEs etc > Flashcards

Common drug SEs etc Flashcards

1
Q

How do you monitor furosemide efficacy?

A

Weight daily

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2
Q

What blood to monitor furosemide?

A

U+Es (hypokal)

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3
Q

If oral furosemide isn’t working what can you try?

A

IV better bioavailability

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4
Q

If furosemide is given BD what timings?

A

morn and lunch (at night- nocturia)

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5
Q

Do you worry about first dose hypotension in diuretics?

A

Not so much

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6
Q

When in the day should you give nitrates?

A

morn and lunch- need a nitrate free period as get tolerance

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7
Q

When should you give first dose of ramipril?

A

Night (first dose hypotension)

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8
Q

Monitoring bloods for ACEi?

A

U&Es and LFTs (pro drug so needs good liver function)

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9
Q

Does someone need to omit ACEi if D&V

A

Yes possibly- sick day rules- to call doc

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10
Q

Timings of parkinsons meds?

A

Same time each day

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11
Q

What if parkinson medicated pt is NBM?

A

Convert to rotigotine patch (use website)

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12
Q

When should you take statins? why

A

Night as that is when the enzyme works

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13
Q

Which statin does timing not matter in?

A

Atorvostatin

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14
Q

Any action need to be taken if someone on statin is given amlodipine?

A

Reduce dose of statin

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15
Q

What drink should statin patients avoid?

A

Grapefruit juice

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16
Q

Counselling re SEs for statin?

A

Rhabdomyolysis

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17
Q

Common metformin SE?

A

GI

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18
Q

Why is metformin MR?

A

So plasma drug level stable for SEs

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19
Q

What if metformin patient has decline in eGFR?

A

Stop the metformin and monitor BMs

20
Q

Digoxin + hypokalaemia =?

A

risk toxicity

21
Q

If converting digoxin or phenytoin from tablet to liquid form what needs to be done

A

reduce dose

22
Q

Vancomycin loading dose is based on?

A

weight

23
Q

Vancomycin maintenance dose is based on?

A

Creatinine clearance

24
Q

Methotrexate patients should avoid which drugs? why?

A

NSAIDs and penicillins as they reduce clearance of MTX

25
Q

How is MTX given?

A

Weekly with folic acid on the other days

26
Q

When do you give a reduced dose of paracet?

A

Pt <45kg (max dose is 15mg/kg)

27
Q

How do you give paracet in liver impairment?

A

max 3g/day

28
Q

What does the number mean in an insulin name e.g. humalog mix 25

A

The amount of short acting in it

29
Q

Do they still need long acting insulin if on a sliding scale?

A

Yes but at 80% dose

30
Q

What insulin will the sliding scale be?

A

Actrapid

31
Q

What is the route of insulins? Except?

A

All SC except fast acting in a sliding scale (Actrapid/novorapid) which are IVI

32
Q

Are oral antibiotics ever used in neut sepsis?

A

No not enough- IV probably tazocin and gent

33
Q

Which antiemetic is fine to use in parkinsons as it doesn’t cross the BBB?

A

Domperidone

34
Q

What must always be tried before giving IV GTN in ACS?

A

Sublingual

35
Q

Name three LMW heparins

A

Enoxaparin, tinzaparin, dalteparin

36
Q

Can ACEi be used in pregnancy?

A

No - labetalol instead

37
Q

Do sulfonylureas carry a risk of hypoglycaemia?

A

Yes

38
Q

What do you need to test before starting a statin?

A

ALT

39
Q

What drug is given in acute dystonic reaction to antipsychotics? When is it NOT given?

A

procyclidine

Tardive dyskinesia

40
Q

Which antihypertensives are contraindicated in PVD?

A

β blockers can cause peripheral vasoconstriction and worsen ischaemia in PVD

ACEi cautioned in severe

41
Q

What can’t you use verapamil with?

A

beta blockers (bradycardia)

42
Q

Can you give CCBs in heart failure?

A

Should avoid except amlodipine

43
Q

What drug can increase risk of rhabdo on a statin?

A

Gemfibrozil

44
Q

What route might be avoided in anticoagulated pt?

A

IM

45
Q

What do you do if statin causes Cr to be 5x normal range?

A

Stop it and if symptoms resolve re-start and lower dose

PSA revision (3 decks)

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