Common Antineoplastics: Administration Route

Question 1

Bendamustine (Treanda)

Answer 1

IV

Question 2

Cyclophosphamide (Cytoxan)

Answer 2

IV or Oral

Question 3

Carboplatin (Paraplatin)

Answer 3

IV. When given with a Taxane, should be given last to reduce toxicities.

Question 4

Cisplatin (Platinol)

Answer 4

IV. When given with a Taxane, should be given last to reduce toxicities. Must give anti-nausea and vomiting pre-meds and extra hydration during treatment.

Question 5

Oxaliplatin (Eloxatin)

Answer 5

IV. Only compatible with D5W.

Question 6

Irinotecan (Camptosar)

Answer 6

IV

Question 7

Topotecan (Hycamtin)

Answer 7

IV

Question 8

Doxorubicin HCl (Adriamycin)

Answer 8

IV. Has a lifetime dose limit due to potential damage to the heart.

Question 9

Doxorubicin Liposomal (Doxil)

Answer 9

IV. Has a lifetime dose limit due to potential damage to the heart.

Question 10

Etoposide (VP-16, Vepesid, Toposar)

Answer 10

IV and Oral. Longer infusions can decrease the chance of low BP.

Question 11

Vincristine (Oncovin)

Answer 11

IV

Question 12

Docetaxel (Taxotere)

Answer 12

IV

Question 13

Paclitaxel (Taxol)

Answer 13

IV. When used with platinums, give first to decrease toxicities.

Question 14

Paclitaxel protein-bound (Abraxane)

Answer 14

IV. Does not need to be given before platinum analogues.

Question 15

Pemetrexed (Alimta)

Answer 15

IV. Must be given with Folic Acid and B12 to decrease myelosuppression.

Question 16

Azacitidine (Vidaza)

Answer 16

IV, SubQ.

Question 17

Decitabine (Dacogen)

Answer 17

IV. Should be prepared using cold infusion fluids to prolong stability.

Question 18

Fluorouracil (5-FU, Adrucil)

Answer 18

IV. Given with Leucovorin to increase effectiveness.

Question 19

Gemcitabine (Gemzar)

Answer 19

IV. Infusion is no longer than 30 minutes to decrease toxicities.

Question 20

Arsenic Trioxide (Trisenox)

Answer 20

IV

Question 21

Bleomycin Sulfate (Blenoxane)

Answer 21

IV, IM, SubQ.

Question 22

Mitomycin (Mitozytrex, Mutamycin)

Answer 22

IV