Common Antidote to Common Toxicities Flashcards
Acetaminophen
N-acetylcysteine (replenishes glutathione)
AChEinhibitors,organophosphates
Atropine >pralidoxime
Amphetamines(basic)
NH4Cl (acidify urine)
Antimuscarinic,anticholinergicagents
Physostigmine salicylate, control hyperthermia
Benzodiazepines
Flumazenil
?-blockers
Glucagon
Carbonmonoxide
100% O2, hyperbaric O2
Copper,arsenic, gold
Penicillamine
Cyanide
Nitrite + thiosulfate, hydroxocobalamin
Digitalis(digoxin)
Anti-dig Fab fragments
Heparin
Protamine sulfate
Iron
Deferoxamine, deferasirox
Lead
EDTA, dimercaprol, succimer, penicillamine
Mercury,arsenic,gold
Dimercaprol (BAL), succimer
Methanol,ethylene glycol(antifreeze)
Fomepizole >ethanol, dialysis
Methemoglobin
Methylene blue, vitamin C
Opioids
Naloxone, naltrexone
Salicylates
NaHCO3 (alkalinize urine), dialysis
TCAs
NaHCO3 (plasma alkalinization)
tPA,streptokinase,urokinase
Aminocaproic acid
Warfarin
Vitamin K (delayed effect), fresh frozen plasma (immediate)