COMLEX Flashcards
humeral shaft frx damages which nerve
radial
frx of medial epicondyle damages which nerve
ulnar
pain over anatomical snuffbox
scaphoid frx
surgical neck of humerus frx damages which nerve
axillary
radial nerve damage –>
wrist drop
ulnar damage –>
last 1.5 fingers numb
median damage –>
first 3.5 fingers numb
why do preggers get GDM?
human placental lactogen (aka chorionic somatomammotropin) increases insulin resistance
tests if you think its B12 def
MMA + homocysteine
CSF in neisseria meningitis
low glucose
high protein
high WBC
xanthochromia
yellow CSF
subarachnoid hemorrhage
abdominal pain after pancreatitis tx
think pseudocysts
pancreatic pseudocyst tx
NPO + observation
todd’s paralysis
post seizure
transient (min - hours)
hands, arms or legs
hemochromatosis heart problems
restrictive CM (low voltage EKG) dilated CM (cardiomegaly)
ASA overdose tx
alkalization of urine (sodium bicarb)
w/in an hour can go gastric lavage
LBP radiates to butt/thighs
better in flexion/sitting
worse in stand/walk
spinal stenosis
dx spinal stenosis
MRI
long term tx for spinal stenosis
weight loss
what do you give to kids that only get breast milk
Vit D starting after birth
iron after 4 mo
tx for GDM
- lifestyle
2. + insulin or glyburide
corkscrew sign on upper GI series
midgut volvulus
what will you see on EKG for LVH
voltage > 5 large boxes
long car ride –> back pain, can’t sit up
psoas syndrome
psoas syndrome tx
upper lumbar spine
then psoas
steps to dx C. diff
- C. diff toxin PCR (comes back in an hour)
- C. diff toxin EIA assay (comes back in 24 hrs) – more specific
- colonoscopy/sig if both neg but high suspicion
internal vs external validity
internal: valid to the pop being studied
external: generalizable
gout vs pseudogout
pseudo + birefringent crystals (blue rhomboids)
musty smelling baby
PKU
girl toddler loses speech, autism-y, hand mvmts
Rett
when do you do tympanometry
asx middle ear effusions
pheo 10s
10% recur post surg 10% familial 10% b/l 10% extra adrenal 10% malignant 10% kids
when is post op fever ok (no workup)
first 48 hrs
variants of langerhans
eosinophilic granuloma
Hand-Schuller Christian (kids)
Letterer-Siwe (infants < 2)
best confirmatory test for Graves
radioiodine uptake scan
newborn: bulging abdomen, cryptorchidism, renal dysplasia/dilated ureters, pulm hypoplasia
prune belly syndrome
dandruff aka
seborrheic dermatitis
rhabdo management
IV fluids, EKG
wilsons tx
penicillamine
pheo, clear cell renal carcinoma, hemangioblastomas
von Hippel Lindau
ST elevations in I, aVL and V5-6: what kind + which vessel
lateral MI (left circumflex)
ST elevations in II, III and aVF: what kind + which vessel
inferior MI (right main coronary)
ST elevations in V1-V4: what kind + which vessel
anterior MI (left anterior descending)
rocker bottom feet
tri 13 (Patau) tri 18 (Edwards)
polydactyly in infant
tri 13 (patau)
clenched fist in infant
tri 18 (edwards)
infant w/ infections, petechiae, dry skin
wiskott-aldrich
unilateral, foul smelling nasal discharge (kid)
foreign body (kids are gross)
drug a/w rash in mono pts
amoxicillin or ampicillin
most important thing to give CKD pts who need contrast studies
vigorous hydration (N-acetylcysteine is good but less vital)
what kind of pneumothorax do you get when you change pressures on ventilation pts?
tension pneumo (same as with penetrating trauma)
which way does trachea deviate w/ tension pneumo?
opposite
distal limb weakness, decreased proprio, decreased DTRs, spinal deformities, pes cavus
charcot-marie-tooth
how much folic acid for preggers
normal: 0.4 mg
high risk: 4 mg
HIV defining illnesses
CIN II/III/carcinoma in situ
bacillary angiomatosis
shingles
thrush
AIDS defining illnesses
esophageal/tracheal/pulmonary candidiasis
intestinal isosporiasis/cryptosporidiosis
karposi’s
cerebral lymphoma
PCP
cerebral toxo
invasive cervical CA
why no cervical HVLA in downs
weakness of alar and transverse ligaments
ipsilateral dilated pupil: what herniation
uncal (supratentorial)
AMS, bleeds, cheyne-stokes breathing: what herniation
central
resp and cardiac dysfunction: what herniation
tonsillar herniation (aka downward)
what does negative predictive value mean?
chances that a neg result is actually negative (true negs/total negs)
what is electrical alternans
big QRS then smaller QRS (seen in cardiac tamponade)
when to give RhoGAM
28 wks
Still’s technique: direct or indirect?
start indirect, finish direct
timeline: baby blues vs depression?
2 weeks
FAP gene
APC
HNPCC/Lynch gene
DNA mismatch repair gene mutation
tx: whooping cough
macrolide (azithromycin, erythromycin or clarithromycin)
> 1: w/in first 3 wks of cough
< 1: w/in first 6 wks of cough
OCD vs OCDPD
OCD has some insight and is upset by it
gold standard for PE dx
pulmonary angiogram
therapeutic INR post DVT
2.0 - 3.0
tx: diverticulitis
quinolone + MTZ
TMP-SMX + MTZ
amoxicillin-clavulanate
patchy, oval hair loss of scalp or generalized loss of body hair
alopecia areata
when to add insulin to DM pt
> 8.5 A1C
COPD tx
combo:
LABA + inhaled glucocorticoid (need both)
most specific lupus tests
anti ds DNA
anti Smith
vasovagal syncope AKA
neurocardiogenic syncope
TCA cardio problems on EKG
widened QRS
prolonged PR
prolonged QTc
sinus tach
1st line tx: persistent allergic rhinitis
intranasal corticosteroids
fat embolism triad
resp changes (tachypnea, cough, hypoxia) neuro changes petechial rash
parasternal lift sign of
right ventricle dilation
how do you look for bence jones
urine protein electrophoresis
GI stromal tumor: Tx
imatinib
what do you test for in 21-hydroxylase def
17-hydroxyprogenterone
how to avoid non-hemolytic febrile transfusion reaction
use leukocyte washed blood products
what do you do when morning glucose is high?
test again at 3 am to differentiate btwn somogyi (will be hypoglycemic) and dawn effect (will be hyperglycemic)
what do you do for dawn effect
give more basal insulin @ dinner
ascites tx
furosemide and/or spironolactone
cord compression tx
corticosteroids
thyroid cancer a/w elevated calcitonin
medullary
bleed where you get better for a while then crash
epidural
MC pancreatic CA location
pancreatic head
tx: croup w/ resp distress
aerosolized racemic epi
criteria to determine severity/mortality of pancreatitis
Ranson criteria
Ranson criteria
poor prognosis: age > 55 WBC > 16,000 glucose > 200 LDH > 350 AST > 250
multifocal atrial tachycardia criteria
3+ diff P-wave morphologies in a single lead
HR > 100
wandering pacemaker criteria
3+ diff P-wave morphologies in a single lead
HR < 100
quad screen
triple screen + inhibin A
hCG, unconjugated estriol, AFP, inhibin A
quad screen results: + for Downs
decreased AFP
decreased estriol
increased inhibin
increased hCG
management: screening for downs
low risk can get triple screen
high risk (>35, late prenatal) get quad
if + –> genetic counseling
then offer amniocentesis
pregger: fever, abd pain and sausage shaped mass near umbilicus
septic pelvic pain thrombophlebitis
pregger/laboring: fever, tachy, tender uterus, foul smelling amniotic fluid
chorioamnionitis
post partum pelvic pain, foul smelling lochia
endometritis
schizos by time
2+ of schizo things
1-6 mo: schizophreniform
6+ mo: schizophrenia
tx: superficial thrombophelebitis
NSAIDs, elevation, heat, compression stockings
superficial vs suppurative thrombophlebitis
superficial + fever/chills and hx of IV cannulation
reasons to commit pts to psych
danger to self
danger to others
inability to care for themselves due to psych illness
SVT management
stable: vagal maneuvers and adenosine. diltiazem/labetalol for rate control
unstable: synchronized cardioversion
breast mass management
age > 30 –> mammo
if look malignant –> sterotactic bx
age < 30 –> U/S
cystic –> aspirated
fibroadenoma –> < 5 = obs; > 5 = FNA bx
non-fibroadenoma –> bx
signs of malignancy in mammo
breast asymmetry
clustered calcification
increased density
mass w/ irregular borders or spiculation
MCC prepubertal short stature and pubertal delay
constitutional growth delay (parents usually “late bloomers”)
delayed puberty definition
girls: > 12 w/o breast growth
boys: > 13 w/o testicular growth
cleft lip management
repair w/ surgery @/by 3mo
cleft palate management
prescribe special nipple for feeding
repair w/ surgery @ 9+ months
aspiration pneumonia – where do you see it? which kids?
R lung > L lung
neuro impaired kids :(
cough/tachypnea < 8 wks old
think chlamydia trachomatis
MCC CAP in kids (+tx)
strep pneumo, amoxicillin/amp or ceftriaxone
guts on the outside of baby
w/o membrane: gastroschisis
w/ membrane: omphalocele
management: omphalocele
- thorough inspection for other congenital defects
2. eventual surgery
vag bleeding 20+ weeks: painless vs painful
painless = placenta previa or vasa previa painful = placental abruption
dx: lactose intolerance
hydrogen breath test
pulsatile liver
cor pulmonale
cor pulmonale CXR
dilated R atrium/ventricle
enlarged central pulm arteries
cor pulmonale EKG
R vent hypertrophy
R axis dev
RBBB
peaked P waves in lead II
steps of asthma control
- SABA prn
- low-dose ICS
- med-dose ICS
- med-dose ICS + LABA or montelukast
- hi-dose ICS + LABA or montelukast
- hi-dose ICS + LABA or montelukast + oral corticosteroids
tx: akathisia (also wtf is it)
(restlessness a/w antipsych meds)
lower/switch psych meds
beta blocker or benzo
if not, benztropine
poison: drooling, mouth burns, dysphagia, vomiting
drain cleaner
poison: AMS (lethargy/coma), tachypnea, anion gap acidosis, Ca oxalate cystalluria (late)
ethylene glycol
where TF do you find ethylene glycol
antifreeze or hydraulic brake fluid
poison: diarrhea, urinary incontinence, miosis, muscle weakness, bronchospasm, bradycardia, emesis, lacrimation, salivation
DUMMBBELS
organophosphates
poison: resp distress, gagging, choking, hypoxia, cyanosis, CNS depression
gasoline
poison: AMS (leth/coma), vision loss, anion gap acidosis
methanol
where do you find methanol
industrial solvents, pain thinner, moonshine (done wrong)
management: kid ingested something caustic
EGD
tx: ethylene glycol poisoning
fomepizole
tx: methanol poisoning
fomepizole
MC location for anal fissure
posterior midline
tx: anal abscess
MTZ
tx: anal fissures
more fiber sitz bath NG ointment topical CCBs botulinum toxin injections recurrent --> lateral internal sphincterotomy
CXR: silicosis (from mining/sand blasting/glass work, etc)
nodular opacities in upper lobe
tx: silicosis
glucocorticoids
CXR: berylliosis (from nuclear power/metalwork/aerospace
b/l hilar adenopathy (same as sarcoid)
tx: berylliosis
glucocorticoids
CXR: asbestosis (from shipbuilding, insulation, demolition)
b/l opacities w/ pleural plaques
straight leg raise AKA
Lasegue’s
FABERE test AKA
Patrick’s
terrible triad
ACL
MCL
medial meniscus
how do you get the renal part of hepatorenal syndrome
cirrhosis –> vasodilation
down SVR
kidneys kick in to help –> renal vasoconstriction –> down GFR/renal fail
how to evaluate osteomyelitis tx response
ESR and CRP
possible problems with babies from DM moms
resp distress syndrome hypertrophic CM (elevated insulin) hypoglycemia (elevated insulin) hypocalcemia (low PTH) polycythemia (hi EPO) hypomagnesemia (Mg excreted by mom kidneys) hyperbilirubinemia (increased hemolysis)
poison: tremor, ataxia, asymmetric sensory deficits, delirium
mercury
tx: mercury poisoning
dimercaprol
MCC elevated maternal serum AFP
dating error
nature crap someone may be taking that messes with warfarin levels
St. John’s wort
also extra leafy greens or whatever
ginko biloba risks
good freaking lord
lower seizure threshold and increase bleeding problems (anti-platelet)
mycosis fungoides
MC cutaneous T-cell lymphoma:
erythematous plaques + lymphadenopathy
which is more common hemophilia A or B
A
meralgia paresthetica: wtf is it
entrapment of lateral femoral cutaneous nerve
–> numb/tingle in superior, lateral thigh
worse w/ stand/walk
tap inguinal or extend thigh to reproduce
tx: narcolepsy
modafinil (daytime sleepiness)
fluoxetine or venlafaxine for cataplexy
levels in Wilsons
ceruloplasmin decreased (use for dx)
total serum Cu decreased
free serum Cu increased
urinary Cu increased
causes of pericarditis
infection (rheumatic fever, coxsackie)
uremia
lupus (or drug induced lupus)
MI
tx: SIADH
fluid restriction
test for pituitary adenomas
MRI
tx: acromegaly
transsphenoidal resection
which vessel stroke –> face blindness
posterior cerebral artery
first step: suspect endocarditis
blood cx (before abx)
anti-centromere abs
CREST
anti-histone
drug induced SLE
anti-mitochondrial
primary biliary cirrhosis
anti-Smith
SLE
anti-smooth muscle
autoimmune hepatitis
FEV1/FVC for obstructive
< 80
ATN FENa (fractional excretion of Na)
> 2%
granular or muddy brown casts
ATN
Q-angle vs valgus/varus
Q angle up –> valgus (knock-kneed)
Q angle down –> varus (bow-legged)
sickle cell kidney problems
renal papillary necrosis
renal papillary necrosis UA
necrotic tissue
tx: psoriasis
topical corticosteroids
severe (>10% body): UVB
extreme: acitretin + UVB/PUVA
fine white lacy lesions in mouth (name and dz)
Wickham striae
lichen planus
tx: prolactinoma
cabergoline or bromocriptine
(try one then the other)
if neither work –> transsphenoidal resection
tx: sigmoid volvulus
nontoxic: endoscopic decompression + elective sigmoidectomy later
toxic/ischemia: Hartmann’s procedure (sigmoidectomy + colostomy)
kid w/ pancytopenia, recurrent infections, thumb abnormalities, cafe-au-lait spots, renal abnormalities and short stature
fanconi anemia
who’s got cafe-au-lait spots?
NF 1
McCune-Albright
Fanconi anemia
Bloom syndrome
inflammation and narrowing of intrahepatic and/or extrahepatic bile ducts (bead pattern on cholangiography)
primary sclerosing cholangitis
pts w/ primary sclerosing cholangitis @ risk for
UC
hepatic adenoma RFs
OCPs
anabolic steroids
glycogen storage dz
when to resect hepatic adenomas
symptomatic
or > 5 cm
or don’t get smaller when stop OCPs
what drugs do you get post MI
BB* ACE* Statin ASA (+clopidogrel if stented) * improves mortality
tx: transudative pleural effusion
thoracentesis
tx: empyema
chest tube + empiric abx
thyroid levels in preggers
TBG increases so total and bound T4/Ts increase
TSH may go down since hCG is close
free thyroxine is unchanged
dx: syphilis
primary: dark field microscopy or direct florescence Ab testing (lesion tissue)
secondary/tertiary: RPR, VDRL; confirm with fluorescent treponemal Ab absorbed test (FTA-ABS)
Neurosyph (CSF): VDRL best
tx: syphilis
1/2: penicillin G (1 dose)
latent: 3 doses
neurosyphilis: continuous infusion
dx: osteomyelitis
initial: x-ray (periosteal elevation)
most sensitive: MRI
most accurate: bx/cx (chose abx)
tx: fibroids
GnRH agonists (shrinks them) definitive: hysterectomy or myomectomy (depend on kid-wanting)
tx: PE
IV heparin (if stable) tPA (if unstable)
chvostek sign means
hypocalcemia
hypocalcemia EKG
prolonged QT
what changes w/ warfarin (BT/PT/PTT)
increased PT
cranial/sacral mvmt
as cranium (occiput) flexes, sacrum extends (counternutates)
when to use the apt test?
diff btwn fetal/maternal blood: neonatal hematemesis, maternal GI/vaginal bleeding
what changes w/ DIC (BT/PT/PTT)
acute: increased PT and PTT (and increased d-dimer)
chronic has normal PT/PTT
tx: molluscum contagiosum
self limiting, do nothing
management: acetaminophen poisoning
1st hour: give activated charcoal
if after that: take serum levels @ 4, 6, 8 hrs to see if need N-acetylcysteine
> 8 hrs after: N-acetylcysteine
spike and dome BM on renal bx
membranous glomerulonephritis
painless jaundice w/ palpable GB (sign and path)
courvoisier’s
pancreatic adenocarcinoma
where to treat CAP?
use CURB-65 score: Confusion Uremia (BUN >20) RR (> 30) BP (sys < 90 or dia < 60) Age > 65
< 2 = outpatient
2 = inpatient
3+ = ICU
tx: CAP
azithromycin or moxifloxacin
add beta-lactam if in ICU
newborn male w/ urinary tract obstruction
usually posterior urethral valves
dx: posterior urethral valves (newborn)
voiding cystourethrogram
tx: mobitz type II AV block
if symptomatic: pacemaker
fall on outstretched hand –> what SD
posterior radial head (pronates)
nephropathy after viral illness, normal C3, IgA and C3 on staining
IgA nephropathy
renal bx: lumpy bumpy pattern on microscopy
post-strep glomerulonephritis
PSGN C3 level
low
IgA nephropathy C3 level
normal
fusion of podocyte foot processes
minimal change disease
deafness and hematuria
alports
kimmelstiel-wilson nodules
diabetic nephropathy
kidney thing a/w HIV
focal sclerosing glomerulonephritis
renal bx: apple green birefringence w/ congo red stain
amyloidosis
renal bx: tram track BM
membranoproliferative nephropathy
nephropathy a/w Hep C
membranoproliferative nephropathy
also can be membranous
MCC epididymitis
< 35: chlamydia
older: e. coli
levels in polycythemia vera
low EPO
increased RBC, WBC, platelets, bilirubin, B12, uric acid
tx: polycythemia vera
phlebotomy + hydroxyurea
DEXA results
-1 to - 2.5: osteopenia
< -2.5: osteoporosis
MCC spontaneous bacterial peritonitis
E. coli
classic (but not MC) PE EKG finding
S1-Q3-T3
S wave in I
Q and inverted T in III
management: thyroid nodule
- get TSH
2a. TSH normal/high (hypoTh)–> FNA (if > 1 cm)
2b. TSH low (hyperTh)–> scintigraphy
tx: 3rd degree burn
excision and skin grafting
when to tx shingles
give -cyclovirs w/in 72 hours of lesion appearance
pain management always
tx: NMS
- stop med
- IV fluids
- dantrolene/bromocriptine/amantadine
criteria to dx fibromyalgia
TPs above and below waist on both sides
tx: fibromyalgia
duloxetine
milnacipran
pregabalin
MCC meningitis: born to 3 mo
GBS
MCC meningitis: 3 mo - 9 year
strep pneumo