combo drugs

Question 1

effect of nitrates

Answer 1

incr HR, contractility, coronary blood flow

decr BP, periph resistance, coronary resistance, wall tension

Question 2

effect of calcium channel blockers

Answer 2

decr HR, BP, contractility, periph resistance,coronary resistance, wall tension

incr coronary blood flow, HR

Question 3

effect of beta blockers

Answer 3

decr HR, contractility

incr coronary resistance

no eff wall tension

Question 4

nitrates + calcium channel blockers

Answer 4

incr HR (reflex)

signif incr coronary blood flow

signif decr BP, periph resistance coronary resistance

no effect on contractility

Question 5

nitrates + beta blockers

Answer 5

decr contractility, wall tension

no eff HR, coronary resistance

Question 6

calcium channel blockers+ beta blockers

Answer 6

decr HR, contractility, wall tension, coronary resistance

Question 7

what are the AV blocker drugs

Answer 7

beta blockers

calcium channel blockers

both decr Ca2+ current and repol, incr refractory period

Question 8

when is AV blockers contraindicated

Answer 8

1) LV dysfunction (HF) b/c decr contractility and HR
2) AV block
3) patient on digitalis