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RESP 208, Clinical Application & Concepts in Critical Care II > Combined Adrenergic and Anti-Cholinergic Bronchodilators > Flashcards

Combined Adrenergic and Anti-Cholinergic Bronchodilators Flashcards

1
Q

Name the 6 Combined Adrenergic and Anti-Cholinergic Bronchodilators

Generic Names (6)

A
  1. Ipratropium Bromide/Albuterol
  2. Aclidinium Bromide/Formoterol
  3. Glycopyrrolate Bromide/Formoterol
  4. Glycopyrrolate Bromide/Indacaterol
  5. Umeclidinium Bromide/Vilanterol
  6. Tiotropium Bromide/Olodaterol
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2
Q

Name the 6 Combined Adrenergic and Anti-Cholinergic Bronchodilators

Trade Names (6)

A
  1. SVN: DuoNeb, MDI: Combivent
  2. Duaklir Pressair
  3. Bevespi Aerosphere
  4. Ubitron Neohaler
  5. Anoroa Ellipta
  6. Stiolto Respimat
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3
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators

What are the Receptors

A

Muscarinic and B2

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4
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators

What is the Mode of Action

A

Muscarinic: Blocks “ACH” Acetylcholine from binding to “M” Muscarinic Receptors causing dilation of Airways

B2: Relaxes bronchial smooth muscles, and stimulates mucociliary activity

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5
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators

What is the Duration

A

6 - 24 Hours

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6
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators

What are the Hazards (10)

A
  1. Increase HR
  2. Increase BP
  3. Tremors
  4. Palpitations
  5. Dizziness
  6. Nervousness
  7. Hypokalemia
  8. Hyperglycemia
  9. Dry mouth
  10. Pupillary Dilation
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7
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators
Ipratropium Bromide/Albuterol

Trade Names
Dosages

A

Trade Names:
SVN: DuoNeb, MDI: Combivent

Dosages:
SVN: 0.5 mg/2.5mg
DPI: 18 mcg/9 mcg/puff 2 puff

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8
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators
Aclidinium Bromide/Formoterol

Trade Names
Dosages

A

Trade Names:
Duaklir Pressair

Dosages:
DPI: 400 mcg/12 mcg inhalation BID

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9
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators
Glycopyrrolate Bromide/Formoterol

Trade Names
Dosages

A

Trade Names:
Bevespi Aerosphere

Dosages:
MDI: 9 mcg/inhalation and 4.8 mcg inhalation indacaterol BID

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10
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators
Glycopyrrolate Bromide/Indacaterol

Trade Names
Dosages

A

Trade Names:
Ubitron Neohaler

Dosages:
DPI: 15.6 mcg/inhalation and 27.5 mcg/inhalation indacaterol BID

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11
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators
Umeclidinium Bromide/Vilanterol

Trade Names
Dosages

A

Trade Names:
Anoroa Ellipta

Dosages:
DPI: Umeclidinium 62.5 mcg/inhalation
and Vilanterol 25 mcg/inhalation, once daily

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12
Q

Combined Adrenergic and Anti-Cholinergic Bronchodilators
Tiotropium Bromide/Olodaterol

Trade Names
Dosages

A

Trade Names:
Stiolto Respimat

Dosages:
SMI: Tiotropium 2.5 mcg/inhalation
and Olodaterol 2.5 mcg/inhalation, 2 inhalations once daily

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RESP 208, Clinical Application & Concepts in Critical Care II (12 decks)

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