Colorectal I Flashcards
What’s a pneumonic for remembering the causes of small bowel obstruction?
“HANG IVs”
Hernias 2%
Adhesions (from previous surgery with formation of intra abdominal adhesions, commonly colorectal and gynaecological surgery)
Neoplasms (malignant, benign, primary or secondary) (5%)
Gallstone ileus
Intussusception
Volvulus
Strictures (eg Crohn’s disease (6%), ischaemia)
If surgery is indicated for SBO, patients should be given antibiotic prophylaxis of which antibiotics? [3]
cefoxitin, or ampicillin plus gentamicin
What is A?
Anal abscess
Anal fissure
Haemorrhoid
Anal fistula
What is A?
Anal abscess
Anal fissure
Haemorrhoid
Anal fistula
An anal fissure is a superficial tear in the skin distal to the dentate line
What does the following best describe?
abnormal tunnel under the skin that connects the anal canal in the colon to the skin of the buttocks
Anal abscess
Anal fissure
Haemorrhoid
Anal fistula
What does the following best describe?
abnormal tunnel under the skin that connects the anal canal in the colon to the skin of the buttocks
Anal abscess
Anal fissure
Haemorrhoid
Anal fistula
Describe the treatment algorithm for acute fissures
1st line: soften stool
- high fibre intak
- Bulk forming laxatives
- lubricants like petroleum jelly
2nd line:
- Glyceryl trinitrate
3rd line:
- topical diltiazem (if headaches from glyceryl trinitrate are too much)
Describe the treatment algorithm for chronic anal fissures [3]
topical glyceryl trinitrate (GTN) is first-line treatment for a chronic anal fissure
Botulinum toxin or sphincterotomy is used after failure of topical treatment for 8 weeks
sphincterotomy:
The operation usually takes about 15 minutes. Your surgeon will make a small cut on the skin near your back passage. They will cut the lower part of the internal sphincter muscle. This will relieve the spasm in the sphincter, allowing a better blood supply to heal the fissure.
almost all diverticula are found in the []
almost all diverticula are found in the sigmoid colon
Describe two symptoms of complications of diverticulitis [2]
pneumaturia or faecaluria may suggest a colovesical fistula
vaginal passage of faeces or flatus may suggest a colovaginal fistula
What might an AXR show in diverticulosis? [3]
AXR: may show dilated bowel loops, obstruction or abscesses
Describe the treatment regime for diverticulitis? [4]
mild cases of acute diverticulitis may be managed with oral antibiotics, liquid diet and analgesia CKS
dicycloverine: antispasmodic
if the symptoms don’t settle within 72 hours, or the patient initially presents with more severe symptoms, the patient should be admitted to hospital for IV antibiotics
Consider open or laparoscopic resection for patients who have recovered from complicated acute diverticulitis but have continuing symptoms (such as stricture or fistula)
What is the name for the staging criteria of colorectal cancer? [1]
Describe each stage [4]
Duke’s classification
Describe the adjuvant chemotherapy given for colorectal cancer: [2]
Describe the biologicals used [3]
Dukes B if poor prognositic factors
Dukes C:
- Fluorouracil (5-FU)
- Capecitabine (first line)
Biologicals:
- Cetuximab (anti-EGFR)
- Panitumubab (anti-EGFR)
- Bevacizumab (anti-VEGF)
State 4 reasons why get referred to the two week cancer pathway for colorectal cancers [5]
Positive FIT test
Over 40 years with abdominal pain and unexplained weight loss
Over 50 years with unexplained rectal bleeding
Over 60 years with a change in bowel habit or iron deficiency anaemia
Any age with rectal or abdominal mass
What is the FOLFOX regime of treating colorectal cancer? [3]
Chemotherapy regime of:
* 5-FU
* Folinic acid
* Oxaliplatin
Which of the following involves removing the sigmoid colon and upper rectum but sparing the lower rectum and anus?
Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy
Which of the following involves removing the sigmoid colon and upper rectum but sparing the lower rectum and anus?
Hartmann’s procedure
High anterior resection
Left hemicolectomy
Low anterior resection
Right hemicolectomy
Describe the topical treatments used for haemorrhoids? [3]
Anusol:
- Chemicals used to shrink
Anusol HC
- As above but with hydrocortisone
Germoloids:
- Lidocaine
Describe the non-surgical treatments used for haemorrhoids? [4]
Rubber band ligation
Injection sclerotherapy
IR coagulation
Bipolar diathermy
PassMed: outpatient treatments: rubber band ligation is superior to injection sclerotherapy
What are the surgical treatment options for haemorrhoids? [4]
Surgical haemorrhoidectomy
Haemorrhoid artery ligation
Staple haemorrhoidectomy
- A 45-year-old man presents with a carcinoma 10cm from the anal verge, he has completed a long course of chemoradiotherapy and has achieved downstaging with no evidence of threatened circumferential margin on MRI scanning.
What is the most appropriate colonic resction for this patient?
Anterior resection with covering loop ileostomy
- ‘carcinoma 10cm from the anal verge’ implies that the anus is unaffected by the cancer. Abdominal-perineal excision of rectum is only used when the anus is involved.
Low rectal cancer is usually treated with a low anterior resection. Contraindications to this include involvement of the sphincters (unlikely here) and poor sphincter function that would lead to unsatisfactory function post resection. Most colorectal surgeons defunction resections below the peritoneal reflection as they have an intrinsically high risk of anastomotic leak. A loop ileostomy provides a safe an satisfactory method of defunctioning these patients. A contrast enema should be performed prior to stoma reversal.
After testing, he is found to be a carrier of the MSH2 gene and is subsequently diagnosed with HNPCC.
Aside from colorectal cancer, which of the following is the patient at greatest risk of developing?
Endometrial cancer
Lung cancer
Medulloblastoma
Pancreatic cancer
Thyroid cancer
After testing, he is found to be a carrier of the MSH2 gene and is subsequently diagnosed with HNPCC.
Aside from colorectal cancer, which of the following is the patient at greatest risk of developing?
Endometrial cancer
Lung cancer
Medulloblastoma
Pancreatic cancer
Thyroid cancer
HNPCC is associated with an increased risk of endometrial cancer, however this patient is male.
A fistula is defined as an abnormal connection between two epithelial surfaces.
What are the two most common causes of fistulae? [2]
diverticular disease and Crohn’s.
Describe how you treat fistulae if:
- No IBD or distal obstruction? [1]
- High-output is excessive? [2]
- Secondary to Crohns? [1]
No IBD or distal obstruction: Conservative management
- High-output is excessive: octreotide (reduces pancreatic secretions); TPN
- Secondary to Crohns: drain acute sepsis; seton placement
Low rectal cancer is usually treated with [] surgery.
How do you adapt ^ to avoid the high risk of anastomotic leak? [1]
What is the contraindication to this? [1]
Low rectal cancer is usually treated with a low anterior resection
- Contraindications to this include involvement of the sphincters
- Most colorectal surgeons defunction resections below the peritoneal reflection as they have an intrinsically high risk of anastomotic leak. A loop ileostomy provides a safe an satisfactory method of defunctioning these patients
What type of stoma is this? [1]
Loop stoma
What type of stoma is this? [1]
Label which of A & B is the proximal and distal part [2]
Double barrel stoma
A: Proximal
B: Distal
Physiological complications of high output ileostomy? [2]
○ > 1.5 - 2 litres
○ Fluid & Electrolyte imbalance
■ Dehydration, AKI
■ ↓Na, ↑K, ↓Mg (Addison’s picture)
■ Vitamin B12, Folate Def.}}
Problems associated with low volume ileostomy? [2]
● Low Volume (↓frequency & or quantity)
○ Stenosis
○ Impending obstruction}