Colon and Appendix Flashcards
colonoscopy is limited by occassional failure to reach the
right colon
large intestine is composed of
cecum, appendix, colon, rectum and anal canal
total length of LI
1.5 m
LI is characterized by
taenia coli, 3 longitudinal bands of muscle that traverse the colon shortening it to form the haustra, the sacculations created by puckering of bowel wall
major functions of LI
formation, transport, evacuation of feces
part of LI that absorb water
cecum, ascending colon
large blind pouch that extends below the level of the ileocecal valve
cecum
cecum lies in the ____ but may be quite mobile
right iliac fossa
cecum is intraperitoneal or extraperitoneal?
usually covered on all sides by peritoneum (intraperitoneal), but may be fixed extraperitoneall, covered only on its ventral surface by peritoneum
worm-like tube that hangs from near the apex of cecum
appendix
consists of 2 lips that project into the cecum forming a sometimes prominent mass
ileocecal valve
ascending colon is intraperitoneal or extraperitoneal
extraperitoneal, lying in the anterior pararenal space, covered only on its ventral surface by peritoneum
curve of hepatic flexure that is closely related to the descending duodenum and right kidney
proximal more posterior curve
hepatic flexure curve that is closely related to the gallbladder
distal anterior curve
transverse colon is intraperitoneal or extraperitoneal
intraperitoneal and suspended from the transverse mesocolon
limits the superior extent of the small bowel loops
transverse mesocolon
closely related to the tail of the pancreas and caudal aspect of the spleen
splenic flexure
splenic flexure is anchored to the diagphragm by
phrenicocolic ligament
serves as the boundary between processes of the left subphrenic space and left paracolic gutter
splenic flexure
descending colon is intraperitoneal or extraperitoneal
extraperitoneal, within the anterior pararenal space and is covered by peritoneum only on its ventral space
forms a redundant loop of variable length from the distal ascending colon in the left iliac fossa to the rectum
sigmoid colon
sigmoid colon is intraperitoneal or extraperitoneal
completely intraperitoneal and is suspended by sigmoid mesocolon that allows considerable mobility
sigmoid colon penetrates the peritoneum at the level of ____ to continue as the extraperitoneal rectum
S2 to S4
rectum extends for approximately ___ cm in close relationship with the sacrum
12 cm
peritoneum forming the pouch of Douglas covers the ____ and _____ aspects of rectum
ventral and lateral aspects
length of anal canal is ___ cm and is invested by the sphincter ani and levator ani muscles
3 to 4 cm long
a series of vertical folds form the _______, beneath which are the veins that when dilated are hemorrhoids
rectal columns of Morgagni
thickness of the wall of the normal colon does not exceed __ mm
5 mm
generic term for a lesion that protrudes from the mucosal surface of the GI tract
polyps
approximately 50% of colorectal adenocarcinoma occur in the
rectum and rectosigmoid area
approximately 25% of colorectal adenocarcinoma arise from
sigmoid colon
Most colorectal adenocarcinoma are what form and size
constricting annular lesion, 2 to 6 cm in diamter, with raised everted edges and ulcerated mucosa
nearly all cancers of the colon arise from
pre-existing adenomas
infiltrating scirrhous adenocarcinoma tumors are common in
gastric carcinoma
infiltrating scirrhous adenocarcinoma when seen in the LI, is associated with
ulcerative colitis
most frequent complication of colorectal adenocarcinoma
obstruction
conditions with increased risk of colorectal adenocarcinoma
ulcerative colitis, crohn disease, familial adenomatpus polyposis syndrome, Peutz-Jeghers syndrome
Bowler hats sign is seen in
polyps, when viewed obliquely
imaging technique that shows improved detection of lymph node metastases in colorectal adenocarcinoma
Diffusion weighted MR
indicative of tumor extension through the bowel wall
pericolonic fat stranding
size of LN enlargement denoting lymphatic spread of tumor
> 1 cm
major indication of colonoscopy and imaging studies of the colon
detection of colon polyps
rules of thumb in polyps at risk of malignancy
polyps less than 5 mm are almost all hyperplastic, with a risk of malignancy less than 0.5%, polyps 5 to 10 mm size are 90% adenomas, with a risk of malignancy of 1 %. Polyps 10 to 20 mm in size are usually adenomas, with a risk of malignancy of 10%. polyps larger than 20 mm are 50% malignant
polyps that are nonneoplastic mucosal proliferation. they are round and sessile. nearly all are less than 5 mm in size
Hyperplastic polyps
polyps that are distinctly premalignant and a major risk for development of colorectal carcinoma. they are neoplasms with a core of connective tissue
adenomatous polyps
at what age does approximately 5-10% of population have adenomatous polyps
older than 40 years
polyps that represent 1% of colon polyps. they are a common cause of rectal bleeding in children
hamartomatous polyp
Peutz-Jeghers polyp is a type of
hamartomatous polyp
polyps that are usually multiple, and associated with inflammatory bowel disease
inflammatory polyps
inheritance pattern of familial adenomatous polyposis syndrome
autosomal dominant with high penetrance
how many of FAPS are inherited and what portion of the cases are spontaneous
2/3 inherited, 1/3 spontaneous
polyps in FAPS are ____ which are usually evident by age 20
tubulovillous adenomas
recommended therapy for FAPS
total colectomy with rectal mucosectomy and ileoanal pouch construction due to high risk for colorectal cancer
patients with FAPS are at risk of numerous extracolonic manifestations such as
carcinomas of the small bowel, thyroid carcinoma, mesenteric fibromatosis
FAPS patient with associated bone and skin abnormalities including cortical thickening of the ribs and long bones, osteomas of the skull, supernumerary teeth, exostoses of mandible and dermal fibromas, desmoids and epidermal inclusion cysts have been diagnosed as
Gardner syndrome