Collagen Flashcards
Where is type I collagen found?
Found throughout the body except in cartilaginous tissues!
Skin, tendon, vascular, ligature, organs, main component of bone
Which collagen is the most common?
Type I
90%
Where is type II collagen found?
Main component of cartilage
Where is type III collagen found?
Walls of arteries and other hollow organs
Which type of collagen makes up reticulin?
Collagen III
Where is type IV collagen found?
Bases of cell basement membrane
How is collagen synthesised?
RER of cells derived from mesenchyme synthesise procollagen chains
These are combined into a triple helix
They leave the cell
Converted into Tropocollagen
Assembled and cross-linked into fibrils
Fibrils combine to form a fibre!