Cognition Disorders Flashcards

1
Q

Depression- Dx

A
  • 2 + weeks, 5+ sx
  • Depressed mood, weight, appetite change
  • Fatigue, loss of energy
  • Thoughts of death
  • Impairment in work, love and play
  • No bereavement exclusion
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2
Q

Depression- Diff in elders

A
  • Agitation and irritability presenting sx
  • Cognitive complaints, but aware of them, lack of effort
  • Somatization- diffuse pain fatigue or vague complaints
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3
Q

Depression- Tx

A
  • CBT

- SSRIs

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4
Q

Delirium- Definition

A
  • Transient, organic mental syndrome
  • Global impairment of cognitive function
  • Acute
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5
Q

Delirium- Eti

A
  • Post-surg, acute mental illness
  • Meds, alcohol
  • Sleep deprivation
  • Dementia (sundowning)
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6
Q

Delirium- Sx

A
  • Alteration in level of consciousness, variable over the day
  • Inability to shift attention
  • Memory impairment
  • Hyper/ hypo active change in behavior
  • Sundowning
  • Misperceptions, hallucinations, vague delusions
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7
Q

Delirium- Tx

A
  • Tx underlying cause
  • Control envt- visual, verbal cues
  • Well lit envt- cues for sleep wake cycle
  • Neuroleptics- haloperidol
  • No anticholinergics or benzos
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8
Q

Dementia- Eti

A
  • Progressive development of 2+ cognitive deficits
  • Memory, exec fxn, language, visuospatial, personality
  • Interfere with general activities
  • Loss of intelligence
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9
Q

Dementia- sx

A
  • Impaired memory, visuospatial and processing speed
  • Concrete reasoning intact, abstract impaired
  • Agitation
  • Agression
  • Psychosis
  • Depression
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10
Q

Dementia- Dx

A
  • Evidence of significant cognitive decline from previous
  • Concern of individual, other
  • Deficits interfere with daily activities
  • Do no occur exclusively in context of delirium or explained by other mental disorder
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11
Q

Lewy body disease

A
  • Fluctuating cognition with variation in alertness and attention
  • Spontaneous parkinksonism
  • Vivid hallucinations
  • Sleep disorders
  • Severe neuroleptic sensitivity
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12
Q

Frontotemporal dementia/ Pick disease- Sx

A
  • Behavioral disinhibition- hoarding, perseverative, stereotyped behavior
  • Hyperorality and dietary changes
  • Decline in language ability- word creation, word finding, grammar
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13
Q

Depression- Eti

A
  • Prior hx, midst of dementia, delirium

- Deaths, loss of social support & roles

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14
Q

Alzheimers disease

A

Triad:

  • Memory impairment w/ difficulty learning, recalling
  • Visuospatial problems
  • Language impairment interfere with fxn
  • irritability, depression , delusions
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15
Q

Lewy body disease- Eti

A
  • Second most common form of dementia

- Due to abnormal inclusion bodies in brain

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16
Q

Lewy body disease- Tx

A

Don’t use neuroleptics! Increases parkinsonian sx

17
Q

Vascular/ multi-infarct dementia- Eti

A
  • Cerebrovascular disease, mini strokes
18
Q

Vascular/ multi-infarct dementia- Sx

A
  • Dementia sx following stroke
  • Gradual onset with mini strokes
  • Less severe memory impairment
  • Impaired recall, intact recognition
  • Difficulty on speeded tests
  • More severe depression
19
Q

Frontotemporal dementia/ Pick disease- Eti

A
  • Younger onset, 50s

- 25% presenile dementias

20
Q

Frontotemporal dementia/ Pick disease- Dx

A
  • Normal mini-mental exam

- Frontal deficits in verbal fluency, abstraction

21
Q

Reversible causes of dementia

A
  • B12
  • Hematoma, CNS tumor
  • Thyroid
  • Hypercalcemia
  • Alcohol/ drugs
  • Heavy metal toxicity
  • Depression
22
Q

Creutzfeld-Jacob- Eti

A
  • Infectious prion disease
  • Infectious, sporadic and inherited
  • Mad cow, retinal & dura mater transplants
23
Q

Creutzfeld-Jacob- Sx

A
  • Exaggerated startle response, seizure & extra-pyramidal signs
  • Dementia
24
Q

Creutzfeld-Jacob- Dx

A

Characteristic EEG patterns, MRI lesions

25
Q

Dementia- Tx

A

Chlinesterase inhibitors: Donepezil, Rivastigmine and galantamine