Coeliac Disease

Question 1

What is the aetiology of coeliac disease

Answer 1

Gluten Sensitivity

Question 2

How is coeliac disease caused

Answer 2

Genetic predisposition:

HLA B8

Question 3

The 5 steps in clinical presentation

Answer 3

• Increased frequency of Stool
• Pale offensive greasy stool (which floats)
• Change in Bowel habit
• Abdomincal colic
• Weight loss+ Weakness

Question 4

How do we diagnose Coeliac disease

Answer 4

• We find Antibodies in response to Gliadian, Transgluatminase, and endomysium
• Endoscopic Biopsy

Question 5

How do we treat coeliac disease

Answer 5

• Gluten free diet

- corticosteroids

Question 6

Why is coeliac disease harder to manage as diabetic

Answer 6

• Harder to manage blood sugar
• Harder to balance diet
• Managing both –> Depression

Question 7

What is dental relevance of the malabsoprtion caused by coeliac

Answer 7

• Glossitis
• Angular Chelitis
• Burning mouth
• Enamel defects (childhood)

-Anaemia

Question 8

What are some of the symptoms of Coeliac

Answer 8

• Flatluence
• Diarrhea
• Steatthroea
• Abdo PAIN
• Borborygmus(rumbling noise made by intestine)

-Secondary Lactose Intolerance

Question 9

Endocrine issues linked to Coecliac

Answer 9

• Amennorhea
• Infertilitiy
• Impotence
• Delayed periods

Question 10

What extraintestinal issues can Coeliac disease cause

Answer 10

• Anaemia

- Skin disdorder (Dermatitis Herpetiformis macropapular)

Question 11

What whole body effects can the malabsorption lead to?

Answer 11

Osteoporosis
Tooth enamel defects
-CNS+PNS disease
-Panceatic disease
-Internal Haemorrhage