Coeliac Disease Flashcards
1
Q
What is Coeliac Disease?
A
Allergic (T-cell) reaction to gluten, wheat, rye, barley
2
Q
What can coeliac disease result in?
A
Malabsorption
3
Q
What is coeliac disease associated with? (2)
A
HLA DQ2
Autoimmune disease
4
Q
What are the clinical presentations of coeliac disease? (5)
A
Diarrhoea Anaemia Steatorrhoea Weight loss Failure to thrive (children)
5
Q
How would you diagnose coeliac disease? (3)
A
Decreased B12, ferritin
IgA anti-transglutaminases
Duodenal biopsy: villous atrophy, crypt hyperplasia, increased intraepithelial leukocytes
6
Q
What is the first-line treatment for coeliac disease?
A
Gluten-free diet (lifelong)
Patient’s struggle to adhere to this but minimal + inadvertent exposure to gluten has no immediate serious consequences
7
Q
How would you manage coeliac disease? (3)
A
Dietician review
Coeliac UK recommendation
DEXA scan - osteoporotic risk
