Coeliac Disease Flashcards

1
Q

At what ages does coeliac disease tend to present?

A

Infancy

40-60 years

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2
Q

Which genetic factors predispose to coeliac disease?

A

HLA-DQ2

HLA-DQ8

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3
Q

What are the potential symptoms of coeliac disease in children?

A

Failure to thrive
Short stature
Symptoms of vitamin deficiency
Abdo pain / discomfort and bloating

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4
Q

What symptoms of coeliac disease might be apparent In women of child-bearing age ?

A

Spontaneous abortion

Infertility

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5
Q

Describe the presentation and treatment of coeliac crisis

A

Severe watery diarrhoea, hypovolaemia, hypoalbuminaemia, hypocalcaemia, acidosis
Treated with rehydration and correction of electrolyte abnormalities +/- corticosteroids

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6
Q

What are the potential complications of coeliac disease?

A
Osteoporosis
Malignancy
Pancreatitis
Pneumococcal infection
Lack of response to Hep B vaccine
Dermatitis herpetiformis
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