Coeliac Disease Flashcards
At what ages does coeliac disease tend to present?
Infancy
40-60 years
Which genetic factors predispose to coeliac disease?
HLA-DQ2
HLA-DQ8
What are the potential symptoms of coeliac disease in children?
Failure to thrive
Short stature
Symptoms of vitamin deficiency
Abdo pain / discomfort and bloating
What symptoms of coeliac disease might be apparent In women of child-bearing age ?
Spontaneous abortion
Infertility
Describe the presentation and treatment of coeliac crisis
Severe watery diarrhoea, hypovolaemia, hypoalbuminaemia, hypocalcaemia, acidosis
Treated with rehydration and correction of electrolyte abnormalities +/- corticosteroids
What are the potential complications of coeliac disease?
Osteoporosis Malignancy Pancreatitis Pneumococcal infection Lack of response to Hep B vaccine Dermatitis herpetiformis