Coagulation Quiz #1

Question 1

Durin in vitro coagulation, which factor is NOT consumed?
a) Fibrinogen
b) Factor XIII
c) Prothrombin
d) Factor VII

Answer 1

D) Factor VII

Question 2

Factor XII can be activated by?
a) contact with neg charged surfaces
b) kallikrein
c) collagen
d) all of the above

Answer 2

d) all of the above

Question 3

Fibrinopeptides A and B are by products of:

Answer 3

thrombin acting on fibrinogen

Question 4

Prothrombin is converted to thrombin by:

Answer 4

A complex of activated factors X, V,PF3, and calcium

Question 5

Fibrinogen degradation products: 3 things true

Answer 5

-Are cleared by the reticuloendothelial system
-inhibit fibrin formation if present in large amounts
-are formed by the action of plasmin on fibrinogen

Question 6

Urokinase is a

Answer 6

Direct plasminogen activator

Question 7

Stabilization of a fibrin clot requires adequate amounts of:

Answer 7

Factor XIII

Question 8

Patients who have a deficiency of AT, Protein C or Protein S may be hypercoagulable because:

Answer 8

These are important inhibitors of coagulation.

Question 9

Fibrinogen degradation differs from d-dimers because:

Answer 9

D-dimers are fragments from factor XIII crosslinked fibrin molecule

Question 10

Substances that have antiplasmin activity:

Answer 10

-alpha 2 macroglobulin
-alpha 2 antiplasmin

Question 11

Plasminogen activators:

Answer 11

-streptokinase
-urokinase
-vascular endothelium (TPA)

Question 12

Hageman factor

Answer 12

Factor XIII

Question 13

Factor VIII

Answer 13

Anti hemophiliac factor

Question 14

Factor IX

Answer 14

Christmas factor

Question 15

Factor X

Answer 15

Stuart-Prower factor

Question 16

High molecular weight kininogen

Answer 16

Fitzgerald factor