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Pharm Cardiac test > Coagulation > Flashcards

Coagulation Flashcards

1
Q

Types of coagulation drugs

A

Anticoaglants - thins blood
Antiplatelets - thins platelets
Thrombolytic - breaks down blood clots

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2
Q

Types of anticoagulants

A

Heparins
LMW Heparins
Activated Xa factor inhibitor
Coumarins
Direct thrombin inhibitors
Direct inhibitor of factor Xa

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3
Q

Heparin drug

A

Heparin

prevents clotting by activating antithrombin

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4
Q

Heparin special stuff

A

SE: bleeding
Good for everyone
PTT lab necessary
Reversal drug: protamine sulfate

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5
Q

What drug reverses Heparin?

A

Protamine sulfate

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6
Q

Heparin PTT range

A

PTT: 60-80 secs
check every 6 hr

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7
Q

What herbs should be avoided with blood thinners

A

G herbs
Ex: garlic, ginger, ginkgo bilboba

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8
Q

LMW Heparin drug

A

Enoxaparin

At home/ non emergency heparin

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9
Q

Enoxaparin special stuff

A

Same things as heparin
Take once a day subQ

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10
Q

Activated factor Xa inhibitor

A

Fondaparinux

Prevents clotting

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11
Q

Fondaparinux special stuff

A

Same issues as heparin
subQ

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12
Q

Coumarins

A

Warfarin

antagonizes vitamin K

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13
Q

Warfarin special stuff

A

PT and INR labs
taken PO
No liver disorders
Reversal drug: vitamin K

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14
Q

What drug reverses Warfarin?

A

Vitamin K

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15
Q

Foods to avoid while on warfarin

A

Lettuce
Spinach
Cabbage
Broccoli
Brussel Sprouts
Mayonaise
Canola Oil
Soy Bean Oil

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16
Q

Warfarin labs

A

PT: 18-24 secs
INR: 2-3

17
Q

Direct thrombin inhibitors drugs

A

(-gatr-), dabigatran, argatroban

Inhibit thrombin

18
Q

Direct thrombin inhibitors(-gatr-) special stuff

A

Alternative when allergic to heparin
Avoid saw palmetto
Same issues as heparin

19
Q

Direct inhibitor of factor Xa

A

(-xaban), rivaroxaban, apixaban

Inhibits factor Xa, stroke prevention

20
Q

Direct inhibitor of factor Xa(-xaban) special stuff

A

Take same time every day(usually dinner)
Used for: stroke, Afib, postop DVT, or prevention

21
Q

Antiplatelet drugs

A

Aspirin, abciximab, clopidogrel, ticagrelor, dipyridamole

Prevent platelet clumping

22
Q

Antiplatelet special stuff

A

Dont mix with anticoagulant, NSAIDS, alcohol

23
Q

Thrombolytic medication drugs

A

(-plase), Alteplase, tPA

Emergency clot dissolver

24
Q

Thrombolytic medication(-plase) special stuff

A

No bleeding or recent strokes
Monitor for bleeding

Pharm Cardiac test (8 decks)

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