Co-ordination of immunity- tissue specific responses Flashcards
2 levels of immune organisation
basic organisation, which is generally homeostatic in nature
rapid mobilisation- can very quickly change if necessary
3 levels of lymphoid structure
primary- thymus and bone marrow
> produce virgin lymphocytes
secondary- spleen, lymph nodes
> sites for activation of lymphocytes
tertiary- isolated follicles, structures associated w chronic inflammation
> post-natal development, ectopic tissue
MALT, NALT, and GALT
mucosa, nasal, and gut-associated lymphoid tissue
peyer’s patch
lymphoid tissue in the gut
role of the lymph node
adaptive immune responses are initiated, dendritic cells migrate there and can interact with naive T cell populations
mucosal lymphoid structure function
induction of mucosal associated adaptive immune responses, e.g. peyer’s patches
what is the general role of lymph nodes on the scale of the whole immune system?
important in making a fast response- not absolutely necessary for a response at all