Co-ordination of immunity- tissue specific responses Flashcards
2 levels of immune organisation
basic organisation, which is generally homeostatic in nature
rapid mobilisation- can very quickly change if necessary
3 levels of lymphoid structure
primary- thymus and bone marrow
> produce virgin lymphocytes
secondary- spleen, lymph nodes
> sites for activation of lymphocytes
tertiary- isolated follicles, structures associated w chronic inflammation
> post-natal development, ectopic tissue
MALT, NALT, and GALT
mucosa, nasal, and gut-associated lymphoid tissue
peyer’s patch
lymphoid tissue in the gut
role of the lymph node
adaptive immune responses are initiated, dendritic cells migrate there and can interact with naive T cell populations
mucosal lymphoid structure function
induction of mucosal associated adaptive immune responses, e.g. peyer’s patches