co-infection

Question 1

interaction- Listeria, Y. pestis, herpesvirus

Answer 1

latent herpes seems to promote resistance to Y. pestis and Listeria
more macrophage activation due to IFNgamma action

Question 2

zika and dengue viruses

Answer 2

non-specific antibody production due to similar envelope proteins

Question 3

schistosomiasis and hep. C

Answer 3

Th2 polarisation from schistosomiasis- lessens response to hepatitis C (more likely to end up w chronic hepC infection)

Question 4

BCG vaccine

Answer 4

TCR cross-reactivity- TB, leprosy, poxviruses

Question 5

example of bottom-up cross-immunity

Answer 5

competition between worm parasites leading to tapeworms becoming displaced in the gut, further along than it would be during a single infection

Question 6

helminths and malaria

Answer 6

less intense malarial disease due to suppression of inflammatory response, but more growth and intensity of infection

Question 7

impact of HIV on macrophages and what this affects

Answer 7

inhibition at recognition, antigen presentation stage and within the macrophage- various points throughout the detection of TB
impacts TB infection cycle and contributes to the worse infections in HIV infected people

Question 8

impact of TB on HIV

Answer 8

increasing propagation and diversity of HIV-1