CNS Tumors Pathology Flashcards

1
Q

grading of pilocytic astrocytoma

A

WHO grade 1

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2
Q

where are pilocytic astrocytoma usually found

A

optic nerve, cerebellar hemisphere

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3
Q

cystic, solid, GFAP positive, rosenthal fibers

A

pilocytic tumor

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4
Q

mean survival of diffuse astrocytoma

A

6-8 years

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5
Q

diffuse astrocytoma WHO grade ?

A

WHO Grade II

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6
Q

gemistocytic, fibrillary, and r protoplastic

A

diffuse astrocytoma

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7
Q

where are diffuse astromctyomas found often

A

temporal lobes

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8
Q

which type of astrocytoma associated with seizures

A

diffuse astrocytoma

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9
Q

anaplastic astrocytoma

A

WHO Grade III

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10
Q

what is the mean survival of anaplastic astrocytoma

A

3 years

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11
Q

morphology of astrocytes

A

dense, nuclear atypia, proliferation

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12
Q

WHO grade IV

A

glioblastoma

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13
Q

what is the MOST frequent brain tumor

A

glioblastoma

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14
Q

hemispheric white matter, edema, necrosis, and widespread infiltration, nuclear pleomorphism, and pseudopalisades

A

glioblastoma

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15
Q

how does astrocytoma spred

A

subarachnoid (drop metsastasis)

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16
Q

higher grade astrocytoma

A

RB and P16/CDKnA

17
Q

what is treatent for astrocytomas

A

radiation therapy and chemotherapy such as temozolamide

18
Q

oligodendroglioma grade WHO

A

grade II

19
Q

anaplastic oligodendroglioma grade

A

grade III

20
Q

where are oligodendrogliomas ound

A

cerebral hemispheres

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21
Q

halos around tumor nuclei

A

oligodendroglioma