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Block 8 Week 2 Colt > CNS Tumors and Neuropsych Symptoms - Rothrock > Flashcards

CNS Tumors and Neuropsych Symptoms - Rothrock Flashcards

1
Q

what is the most common met to the brain?

A

lung

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2
Q

What are the most common mets to the brain in order?

A

lung
breast
melanoma
GI/GU

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3
Q

GI/GU mets are typically (single/multiple)

A

single

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4
Q

lung, melanoma and tumors of unknown origin typically have (single/mutliple) mets

A

mutliple

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5
Q

Which two lobes are most commonly involved in mets?

A

frontal and parietal

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6
Q

What are the two types of cranial nerve tumors?

A

Acoustic neuroma aka schwannoma

optic nerve glioma

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7
Q

What is the hallmark of extradural mets to the spinal cord?

A

PAIN

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8
Q

What type of primary tumors for intradurally/extramedullary in the spinal cord?

A

meningiomas

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9
Q

What type of primary tumors form intramedullary in the spinal cord?

A

astrocytoma and ependyomas

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10
Q

T/F: there is such a thing as cancerous meningitis

A

true: carcinomatous meningitis

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11
Q

Subacute infectious meningitis is also known as…

A

tuberculous meningitis

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12
Q

What are the common causes of fungal meningitis?

A

cryptococcus

coccidiomycosis

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13
Q

What are the causes of acute bacterial meningitis?

A

bacterial and viral

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14
Q

What are the CSF findings in bacterial meningitis?
Glucose
Protein
WBC

A

Glucose: low to zero
Protein: high (up to a gram)
WBCs: PMNs 100s-1000s

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15
Q

What are the CSF findings in viral meningitis?
Glucose
Protein
WBCs

A

glucose: normal (>50)
protein: high (100-300)
WBCs: lymphs 50-500

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16
Q

What are the CSF findings in tuberculous meningitis?
Glucose
Protein
WBCs

A

Glucose: low: (10-40)
protein: high (100-300)
WBCs: PMNs and lymphs 100-500

17
Q

What are the CSF findings fungal meningitis?
Glucose
protein
WBCs

A

glucose: low (20-40)
protein: high (50-150)
WBCs: lymphs 25-100

18
Q

encephalitis is typically (blank) in etiology

A

viral

19
Q

What causes sporadic enceph?

A

HSV1

20
Q

epidemic encephalitis is (blank)-borne

A

insect borne

21
Q

Describe the CSF in viral encephalitis?

A

low normal or normal; protein elevated; lymphs 10-100s

22
Q

How can you Dx encephalitis via CSF?

A

PCR viral DNA/RNA

brain imaging

23
Q

meningoencephalitis is what?

A

meningitis and encephalitis simultaneously

24
Q

Brain abcesses are normally (singular/mixed) in bacterial etiology

A

mixed

25
Q

What is an opportunistic infx causing brain abscesses in AIDS?

A

toxoplasma gondii

26
Q

What are the ranges of symptoms in brain abscesses?

A

asymptomatic to wildly sympotmatic

27
Q

What is the Tx for a brain abscess?

A

Abx or Abx plus surgery

28
Q

What is the major cause of spinal abscesses?

A

Staph aureus

29
Q

What is the hallmark of an epidural abscess of the spinal cord?

A

PAIN

30
Q

T/F: spinal abscesses can be treated with or without surgery

A

false; neurosurgical emergency

31
Q

How do you Dx toxoplasmosis?

A
  1. Serological via blood or CSF

2. Direct ID of the parasite from peripheral blood, amniotic fluid, or in tissue sections

32
Q

T/F: both oocysts and tissue cysts from toxoplasma transform into tachyzoites after ingestion

A

true

33
Q

Tachyzoites of toxoplasma localize to what type of tissue?

A

neural tissue and muscle

34
Q

The form of toxoplasma present in tissue cysts are…

A

bradyzoites

35
Q

T/F: tachyzoites can cross the placenta and infect the fetus

A

true

36
Q

Are humans with toxoplasma infectious?

A

no, only the animal reservoirs

37
Q

HIV can result in what two brain issues?

A

HIV dementia/encephalopathy

HIV myelopathy

38
Q

What are the opportunistic neuro infections post HIV infx?

A 
syphilitic meningitis
cryptococcal meningitis
toxo abscess 
CMV myelitis
progressive multifocal encephalopathy (PML)>JC virus

Block 8 Week 2 Colt (6 decks)

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