CNS/PNS Flashcards
Large myelinated:
Small myelinated:
Unmyelinated:
Proprioceptive (vibration,position) and motor
Autonomic, non-proprioceptive sensory (light touch, pain, temp)
Pinprick sensation
Cervical plexus (4 major peripheral nerves)
Spinal accessory
Greater occipital
Facial
Cutaneous nerves
Brachial plexus (5 major peripheral nerves)
Axillary Radial Median Musculocutaneous Ulnar
Lumbar plexus (2 major peripheral nerves)
Femoral
Obturator
Sacral plexus (4 major peripheral nerves)
Sciatic
Common fibular
Tibial
Superior and inferior gluteal
Neurapraxia grade 1
Etiology
Injured tissue
Conduction
Clinical findings/recovery
Good prognosis, reversible damage
Minor compression
Myelin
Blocked conduction
Profound motor loss, paralysis lasting days-months, no muscle wasting
Normal to minimal sensory
Axonotmesis grade 2
Etiology
Injured tissue
Conduction
Clinical findings/recovery
Fair prognosis for recovery
Severe compression/crush
Myelin, Axon
Conduction failure
Complete motor loss with sensory involvement OR complete motor loss with normal sensation
Neurotmesis grade 3,4,5
Etiology
Injured tissue
Conduction
Clinical findings/recovery
Grade 3: nerve fiber interruption
- transection, laceration, chemical
- myelin, axon, endonuerium
- conduction failure
- complete motor/sensory loss
Grade 4: nerve fascicle damage, surgical repair required
- transection, laceration, chemical
- myelin, axon, endonuerium, perineurium
- conduction failure
- complete motor/sensory loss
Grade 5: complete transaction, recovery not possible
- transection, laceration, chemical
- myelin, axon, endonuerium, perineurium, epineurium
- conduction failure
- complete motor/sensory loss
Neuropathic pain scale (NPS)
Cutoff score
Greater than 5.53 indicates neuropathic pain
GBS aerobic exercise prescription
Subacute phase:
Chronic phase:
Low to moderate intensity
- 40-60% of heart rate max
- RPE: 12-13
- 20-30 mins, 3-5 x/wk
Moderate to high intensity
- 60-80% of heart rate max
- RPE: 14 to 17
Pernicious Anemia
Vitamin B12 deficiency, neuropathy, weakness, changes in cognition
- post stomach sx is high risk, develop atrophic gastritis
Distal polyneuropathy impairments
- stocking glove sensation loss
- sensory impairments present before motor impairments
- DTRs typically impaired
Korsakoff Syndrome
- thiamine deficiency and excessive alcohol consumption
- chronic version of wernicke encephalopathy
- ataxia, incoordination, executive function, forming memory
- alcoholism specifically can lead to peripheral neuropathy and motor/balance disorders
Peripheral neurogenic mechanism
Pain mechanism
- moves beyond the tissue that was directly injured and is related to activation of nerves anywhere from the exit of the SC to the distal segments of the PNS
Erasmus GBS Outcome Score ( EGOS)
- prognostic factors
-based on (3): age, diarrhea preceding and strength at two weeks
poor prognosis: older age onset (over 60), diarrhea preceding the GBS, strength/disability at two weeks, need for ventilator support, rapid onset, motor response amplitude reduction to under 20% of normal
- good predictor of independent ambulate within 6 months